Computational study of the effects of orthopedic plates on gradient-induced peripheral nerve stimulation under MRI using electromagnetic and neurophysiological modeling

IF 3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Magnetic Resonance in Medicine Pub Date : 2025-02-18 DOI:10.1002/mrm.30470

Lijian Yang, Xiaolin Yang, Hui Ye, Norbert Kaula, Yuanhu Jin, Jianfeng Zheng, Wolfgang Kainz, Ji Chen

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引用次数: 0

Abstract

Purpose

This study investigates the impact of orthopedic plates on peripheral nerve stimulation (PNS) during MRI, focusing on how the presence of implants affects PNS thresholds.

Methods

A combination of anatomical electromagnetic and neurophysiological modeling was utilized. Electromagnetic fields in human body models were simulated, both with and without orthopedic plates. Simulations were performed under x-, y-, and z-axis gradient coils, with plates implanted at two clinically relevant locations. Nerve responses were modeled using an established neurophysiological model.

Results

The presence of orthopedic implants significantly influenced nerve stimulation, leading to reductions in stimulation thresholds of up to 80%. Some of the reduced thresholds were close to the PNS limits outlined in International Electrotechnical Commission (IEC) 60601-2-33, suggesting a considerably reduced safety margin compared to cases without implants.

Conclusion

Orthopedic implants can substantially lower the activation thresholds of nearby nerves, with some thresholds approaching the PNS limits defined in IEC 60601-2-33 for MRI gradient field. This finding indicates a reduced safety margin for patients with implants, highlighting the need for more comprehensive safety assessments.

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利用电磁和神经生理模型计算研究骨科板对MRI梯度诱导周围神经刺激的影响。

目的：本研究探讨骨科钢板对MRI中周围神经刺激（PNS）的影响，重点研究植入物如何影响PNS阈值。方法：采用解剖、电磁和神经生理相结合的建模方法。模拟了带和不带矫形板的人体模型中的电磁场。在x、y和z轴梯度线圈下进行模拟，在两个临床相关位置植入板。神经反应采用已建立的神经生理学模型进行建模。结果：骨科植入物的存在显著影响神经刺激，导致刺激阈值降低高达80%。一些降低的阈值接近国际电工委员会（IEC） 60601-2-33中概述的PNS限值，这表明与没有植入物的情况相比，安全边际大大降低。结论：骨科植入物可显著降低附近神经的激活阈值，部分阈值接近IEC 60601-2-33中关于MRI梯度场的PNS极限。这一发现表明植入物患者的安全边际降低，强调需要更全面的安全性评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Magnetic Resonance in Medicine 医学-核医学

CiteScore

6.70

自引率

24.20%

发文量

376

审稿时长

2-4 weeks

期刊介绍： Magnetic Resonance in Medicine (Magn Reson Med) is an international journal devoted to the publication of original investigations concerned with all aspects of the development and use of nuclear magnetic resonance and electron paramagnetic resonance techniques for medical applications. Reports of original investigations in the areas of mathematics, computing, engineering, physics, biophysics, chemistry, biochemistry, and physiology directly relevant to magnetic resonance will be accepted, as well as methodology-oriented clinical studies.