An update on implication of POSS-based nanocomposites in bone tissue engineering: a review.

IF 3.6 4区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of Biomaterials Science, Polymer Edition Pub Date : 2025-08-01 Epub Date: 2025-02-18 DOI:10.1080/09205063.2025.2455234

Leyla Bagheri, Davoud Jafari-Gharabaghlou, Mohammad-Reza Dashti, Nosratollah Zarghami

{"title":"An update on implication of POSS-based nanocomposites in bone tissue engineering: a review.","authors":"Leyla Bagheri, Davoud Jafari-Gharabaghlou, Mohammad-Reza Dashti, Nosratollah Zarghami","doi":"10.1080/09205063.2025.2455234","DOIUrl":null,"url":null,"abstract":"<p><p>The science of Bone tissue engineering (TE) is quickly progressing. Engineering bone usually applications a synthetic extracellular matrix, cells or osteoblasts that can convert to osteoblasts, and adjusting causes that boost adhesion, distinction, and mineralized bone construction of cells. Extremely porous scaffolds perform an important character in cell planting, propagation, and fresh 3D-tissue construction. Reformative medicine and tissue engineering track a multi-disciplinary approach for the novel substances' development and appliance, to the various tissue defects therapy. The presentation of polyhedral oligomeric silsesquioxane (POSS) in the bio-polymeric scaffold has been shown to develop the biotic attributes of the hybrid combinations. This review focuses on the influence of POSS within the Chitosan (CS), Hydroxyapatite (HA), and zeolite matrixes, scaffold drawing, and the advantages and limitations of the materials mentioned for tissue engineering of bone.</p>","PeriodicalId":15195,"journal":{"name":"Journal of Biomaterials Science, Polymer Edition","volume":" ","pages":"1587-1610"},"PeriodicalIF":3.6000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomaterials Science, Polymer Edition","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/09205063.2025.2455234","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/18 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

The science of Bone tissue engineering (TE) is quickly progressing. Engineering bone usually applications a synthetic extracellular matrix, cells or osteoblasts that can convert to osteoblasts, and adjusting causes that boost adhesion, distinction, and mineralized bone construction of cells. Extremely porous scaffolds perform an important character in cell planting, propagation, and fresh 3D-tissue construction. Reformative medicine and tissue engineering track a multi-disciplinary approach for the novel substances' development and appliance, to the various tissue defects therapy. The presentation of polyhedral oligomeric silsesquioxane (POSS) in the bio-polymeric scaffold has been shown to develop the biotic attributes of the hybrid combinations. This review focuses on the influence of POSS within the Chitosan (CS), Hydroxyapatite (HA), and zeolite matrixes, scaffold drawing, and the advantages and limitations of the materials mentioned for tissue engineering of bone.

查看原文本刊更多论文

基于poss的纳米复合材料在骨组织工程中的应用进展

骨组织工程（TE）是一门发展迅速的科学。工程骨通常应用合成的细胞外基质、细胞或成骨细胞，这些细胞或成骨细胞可以转化为成骨细胞，并调节促进细胞粘附、区分和矿化骨结构的原因。极多孔支架在细胞种植、繁殖和新鲜3d组织构建中发挥着重要作用。改革医学和组织工程为新物质的开发和应用开辟了一条多学科的途径，用于各种组织缺陷的治疗。多面体低聚硅氧烷（POSS）在生物聚合物支架中的存在已被证明可以开发杂交组合的生物特性。本文综述了POSS在壳聚糖（CS）、羟基磷灰石（HA）和沸石基质中的作用，支架绘制，以及上述材料在骨组织工程中的优点和局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Biomaterials Science, Polymer Edition 工程技术-材料科学：生物材料

CiteScore

7.10

自引率

5.60%

发文量

117

审稿时长

1.5 months

期刊介绍： The Journal of Biomaterials Science, Polymer Edition publishes fundamental research on the properties of polymeric biomaterials and the mechanisms of interaction between such biomaterials and living organisms, with special emphasis on the molecular and cellular levels. The scope of the journal includes polymers for drug delivery, tissue engineering, large molecules in living organisms like DNA, proteins and more. As such, the Journal of Biomaterials Science, Polymer Edition combines biomaterials applications in biomedical, pharmaceutical and biological fields.