Remarkable spine erosion in cardiovascular syphilis - Computed tomography reconstruction of a century-old forensic case.

IF 1.5 4区 医学 Q2 MEDICINE, LEGAL
Aleksa Leković, Petar Milenković, Jasmina Stevanović, Slobodan Nikolić
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Abstract

This is the most intriguing museum specimen of cardiovascular syphilis, collected in the Forensic Museum founded by professor Milovan Milovanović (1884-1948) in 1923, the first professor of Forensic Pathology in the newly established University School of Medicine in Belgrade. We aimed to analyze the specimen of an autopsy case from the year 1929 in which severe thoracic spine erosion occurred due to syphilitic aneurism and to demonstrate findings by multi-detector computed tomography (MDCT). The specimen comprises an en-block-eviscerated heart, thoracic aorta, thoracic spine, and posterior segments of the ribs, with a partial section of the heart and a longitudinal section of the aorta. We performed histology and MDCT analyses almost a century after the autopsy and revised the original case documentation. The conducted analyses confirmed the characteristic pathology. Most importantly, MDCT imaging revealed intriguing destruction of the vertebral bodies by the pulsatile saccular aneurysm of the descending aorta. The calcified aneurysm led to the extensive irregular mechanically caused osteolysis of the anterior segments of the several vertebral corpora. After the analysis and revision of the original case documentation, we discussed these findings, as well as additional characteristic autopsy findings in syphilis-related deaths, some of which might be forgotten. The direct close contact of the syphilitic aortic aneurysm with the thoracic spine was preserved. By utilizing postmortem MDCT and 3D reconstruction, we better visualize the thoracic spine bone resorption and alteration: in the time of Milovanović, only roentgenography was available, providing less detail.

心血管梅毒中显著的脊柱侵蚀——一个世纪前法医病例的计算机断层扫描重建。
这是最有趣的心血管梅毒博物馆标本,收藏于米洛万·米洛瓦诺维奇教授(1884-1948)于1923年创建的法医博物馆,他是贝尔格莱德新成立的大学医学院的第一位法医病理学教授。我们的目的是分析1929年的一个尸检病例的标本,该病例因梅毒动脉瘤而发生严重的胸椎侵蚀,并通过多探测器计算机断层扫描(MDCT)证明结果。该标本包括闭塞的去内脏心脏、胸主动脉、胸椎和肋骨的后节,具有心脏的部分切片和主动脉的纵切面。我们在尸检近一个世纪后进行了组织学和多层螺旋ct分析,并修改了原始病例文件。所进行的分析证实了特征性病理。最重要的是,多层螺旋ct成像显示降主动脉搏动性囊状动脉瘤对椎体的破坏。钙化的动脉瘤导致广泛的不规则机械引起的椎体前段骨溶解。在对原始病例文献进行分析和修订后,我们讨论了这些发现,以及梅毒相关死亡的其他特征性尸检发现,其中一些可能被遗忘了。保留了梅毒主动脉瘤与胸椎的直接密切接触。通过使用死后MDCT和3D重建,我们可以更好地看到胸椎骨吸收和改变:在milovanoviki时期,只有x线片可用,提供的细节较少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Forensic Science, Medicine and Pathology
Forensic Science, Medicine and Pathology MEDICINE, LEGAL-PATHOLOGY
CiteScore
3.90
自引率
5.60%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.
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