Sex-based Differences in Complications Following Percutaneous Coronary Interventions.

IF 5.7 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Atherosclerosis Reports Pub Date : 2025-02-17 DOI:10.1007/s11883-025-01278-y

Mirvat Alasnag, Giulia Masiero, Sinjini Biswas, Ing Haan

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Abstract

Purpose of review: The role that sex plays in the incidence and outcomes of PCI related complications is not well understood. The purpose of this review is to highlight the commonly encountered peri-procedural complications and search for any sex differences in the published literature.

Recent findings: Procedure related complications and long-term cardiovascular outcomes remain worse in women. The delayed presentation of women with coronary events and delayed referral for an invasive diagnostic angiogram and subsequent revascularization likely contribute to the worse outcomes. Whether the smaller vessel size, residual Syntax Score, and other biological factors impact periprocedural outcomes is controversial and warrants device and procedure specific research to identify sex differences. Modern day percutaneous revascularization has achieved very high acute procedural success rates and low complication rates with the advent of structured training programs, development of appropriate use criteria and refined devices and technologies in the catheterization laboratory. However, both procedure related complications and long-term cardiovascular outcomes remain worse in women.

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经皮冠状动脉介入术后并发症的性别差异

综述的目的：性别在PCI相关并发症的发生率和结局中所起的作用尚不清楚。本综述的目的是强调常见的围手术期并发症，并在已发表的文献中寻找任何性别差异。最近发现：手术相关并发症和长期心血管结果在女性中仍然更差。女性冠状动脉事件的延迟表现和延迟转诊进行侵入性诊断血管造影和随后的血管重建术可能导致较差的结果。是否较小的血管尺寸、剩余语法评分和其他生物因素影响围手术期结果是有争议的，需要对设备和手术进行特定的研究以确定性别差异。现代经皮血运重建术已经取得了非常高的急性手术成功率和低并发症率，这得益于结构化培训计划的出现，适当使用标准的发展以及导管实验室中完善的设备和技术。然而，手术相关并发症和长期心血管结果在女性中仍然更差。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Atherosclerosis Reports 医学-

CiteScore

9.00

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of this journal is to systematically provide expert views on current basic science and clinical advances in the field of atherosclerosis and highlight the most important developments likely to transform the field of cardiovascular prevention, diagnosis, and treatment. We accomplish this aim by appointing major authorities to serve as Section Editors who select leading experts from around the world to provide definitive reviews on key topics and papers published in the past year. We also provide supplementary reviews and commentaries from well-known figures in the field. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.