Synthesis and Concomitant Polymorphs of Green Fluorescence Protein Chromophore-Anthracene-Based Fluorescent Analogue

Abstract

Controlled variations in fluorescence properties hold significant promise for applications in optical sensors, bioimaging, and advanced display devices. However, constructing multicolor fluorescent systems remains a challenge. In this study, we demonstrate the development of multicolor fluorescence by generating polymorphs of a novel green fluorescent protein chromophore analogue, which exhibits distinct photoluminescence emissions in the solid state. The observed emission variations are attributed to differences in molecular conformation due to variations in π-stacking interactions between the polymorphs. This offers a novel approach to designing materials with tunable fluorescence properties.