Past, present and future epidemiology of echinococcosis in China based on nationwide surveillance data 2004–2022

IF 14.3 1区医学 Q1 INFECTIOUS DISEASES

Journal of Infection Pub Date : 2025-02-14 DOI:10.1016/j.jinf.2025.106445

Xu Wang , Yan Kui , Chui-Zhao Xue , Qian Wang , Can-Jun Zheng , Jiang-Shan Zhao , Ya-Ming Yang , Xiao-Feng Jiang , Qu-Zhen Gong-Sang , Xiao Ma , Yu Feng , Xiang-Lin Wu , Sa Chen , Fan-Ka Li , Wen-Jie Yu , Ben-Fu Li , Bai-Xue Liu , Ying Wang , Li-Ying Wang , Shi-Jie Yang , Jian-Ping Cao

{"title":"Past, present and future epidemiology of echinococcosis in China based on nationwide surveillance data 2004–2022","authors":"Xu Wang , Yan Kui , Chui-Zhao Xue , Qian Wang , Can-Jun Zheng , Jiang-Shan Zhao , Ya-Ming Yang , Xiao-Feng Jiang , Qu-Zhen Gong-Sang , Xiao Ma , Yu Feng , Xiang-Lin Wu , Sa Chen , Fan-Ka Li , Wen-Jie Yu , Ben-Fu Li , Bai-Xue Liu , Ying Wang , Li-Ying Wang , Shi-Jie Yang , Jian-Ping Cao","doi":"10.1016/j.jinf.2025.106445","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>We evaluated the epidemiological characteristics of echinococcosis, a global public health threat, in China to inform global control efforts.</div></div><div><h3>Methods</h3><div>Descriptive, statistical, cluster, spatial, and trend analyses were used to evaluate the epidemiology at national, provincial, and county levels based on 2004–2022 nationwide surveillance data from China.</div></div><div><h3>Results</h3><div>Between 2004 and 2022, China recorded 72,676 cystic echinococcosis (CE) cases, 11,465 alveolar echinococcosis (AE) cases, and 5703 others, with an average annual cases per million (ANpM) of 3.45. Females had a higher incidence (ANpM = 3.87) than males (3.05), with most cases (41.15%) in the 30–49 age group, mainly among herders (38.76%) and farmers (37.82%). Seven provinces (Xizang, Qinghai, Xinjiang, Ningxia, Gansu, Sichuan, and Inner Mongolia) accounted for 98.12% of cases, with the Tibetan Plateau showing the highest rates (ANpMs = 155.51 for CE, 46.95 for AE). Surgery and case fatality rates were 39.45% and 5.23% in key surveillance regions (KSRs). Prevalence among residents (0.20%), livestock (1.33%), rodents (1.30%), and dogs (1.26%) declined with increased control funding in KSRs. Between 2023 and 2030, there will be an estimated 20,096 new cases and 45,323 cases requiring treatment.</div></div><div><h3>Conclusion</h3><div>The prevalence of echinococcosis has been alleviated in China, but significant control challenges remain, requiring sustained and targeted control measures.</div></div>","PeriodicalId":50180,"journal":{"name":"Journal of Infection","volume":"90 3","pages":"Article 106445"},"PeriodicalIF":14.3000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Infection","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0163445325000398","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives

We evaluated the epidemiological characteristics of echinococcosis, a global public health threat, in China to inform global control efforts.

Methods

Descriptive, statistical, cluster, spatial, and trend analyses were used to evaluate the epidemiology at national, provincial, and county levels based on 2004–2022 nationwide surveillance data from China.

Results

Between 2004 and 2022, China recorded 72,676 cystic echinococcosis (CE) cases, 11,465 alveolar echinococcosis (AE) cases, and 5703 others, with an average annual cases per million (ANpM) of 3.45. Females had a higher incidence (ANpM = 3.87) than males (3.05), with most cases (41.15%) in the 30–49 age group, mainly among herders (38.76%) and farmers (37.82%). Seven provinces (Xizang, Qinghai, Xinjiang, Ningxia, Gansu, Sichuan, and Inner Mongolia) accounted for 98.12% of cases, with the Tibetan Plateau showing the highest rates (ANpMs = 155.51 for CE, 46.95 for AE). Surgery and case fatality rates were 39.45% and 5.23% in key surveillance regions (KSRs). Prevalence among residents (0.20%), livestock (1.33%), rodents (1.30%), and dogs (1.26%) declined with increased control funding in KSRs. Between 2023 and 2030, there will be an estimated 20,096 new cases and 45,323 cases requiring treatment.

Conclusion

The prevalence of echinococcosis has been alleviated in China, but significant control challenges remain, requiring sustained and targeted control measures.

Abstract Image

查看原文本刊更多论文

基于2004-2022年全国监测数据的中国棘球蚴病流行病学的过去、现在和未来

目的：我们评估中国棘球蚴病（一种全球性公共卫生威胁）的流行病学特征，为全球控制工作提供信息。方法：基于中国2004-2022年全国监测数据，采用描述性、统计学、聚类、空间和趋势分析对国家、省和县各级的流行病学进行评估。结果：2004 - 2022年，中国共报告囊性棘球蚴病（CE） 72676例，肺泡性棘球蚴病（AE） 11465例，其他5703例，年均发病率为3.45 /百万人。女性发病率（ANpM = 3.87）高于男性（3.05），以30 ~ 49岁年龄组发病率最高（41.15%），以牧民（38.76%）和农民（37.82%）为主。7个省（西藏、青海、新疆、宁夏、甘肃、四川和内蒙古）的病例数占98.12%，其中青藏高原的发病率最高（CE的anpm = 155.51， AE的anpm = 46.95）。重点监测区手术率和病死率分别为39.45%和5.23%。居民（0.20%）、牲畜（1.33%）、啮齿动物（1.30%）和犬（1.26%）的患病率随着防治经费的增加而下降。在2023年至2030年期间，估计将有20,096例新病例和45,323例需要治疗。结论：中国棘球蚴病流行情况有所缓解，但防控工作仍面临重大挑战，需要采取持续、有针对性的防控措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Infection 医学-传染病学

CiteScore

45.90

自引率

3.20%

发文量

475

审稿时长

16 days

期刊介绍： The Journal of Infection publishes original papers on all aspects of infection - clinical, microbiological and epidemiological. The Journal seeks to bring together knowledge from all specialties involved in infection research and clinical practice, and present the best work in the ever-changing field of infection. Each issue brings you Editorials that describe current or controversial topics of interest, high quality Reviews to keep you in touch with the latest developments in specific fields of interest, an Epidemiology section reporting studies in the hospital and the general community, and a lively correspondence section.