Neural risk factors that predict the future onset of binge eating or compensatory weight control behaviors: A prospective 4-year fMRI study.

IF 5.9 2区 医学 Q1 PSYCHIATRY
Eric Stice, Sonja Yokum, Jeff Gau, Heather Shaw
{"title":"Neural risk factors that predict the future onset of binge eating or compensatory weight control behaviors: A prospective 4-year fMRI study.","authors":"Eric Stice, Sonja Yokum, Jeff Gau, Heather Shaw","doi":"10.1017/S0033291724003337","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>We conducted a prospective study to advance knowledge of biological factors that predict the future onset of binge eating and compensatory weight control behaviors because few biological risk factors for eating pathology have been identified.</p><p><strong>Methods: </strong>Adolescent girls free of binge eating or compensatory behaviors (<i>N</i> = 88; <i>M</i><sub>age</sub> = 14.5; [SD = 0.9]) completed functional magnetic resonance imaging tasks assessing individual differences in neural responsivity hypothesized to increase risk for onset of binge eating and compensatory behaviors, along with additional self-report measures, and were assessed over a 4-year follow-up.</p><p><strong>Results: </strong>Elevated responsivity of regions implicated in attention and valuation (dorsal anterior cingulate cortex; ventromedial prefrontal cortex) to thin models and lower responsivity of a reward valuation region (caudate) to anticipated milkshake tastes (which correlated with feeling fat) predicted the future onset of binge eating or compensatory behaviors over 4-year follow-up. Parental history of binge eating and compensatory behaviors, emotionality, weight/shape overvaluation, feeling fat, and elevated BMI also predicted the future onset of binge eating or compensatory behaviors.</p><p><strong>Conclusions: </strong>The evidence that elevated attentional bias for, and valuation of the thin ideal, in combination with lower valuation of high-calorie foods, predicted the future onset of eating-disordered behaviors are novel findings. The evidence that weight/shape overvaluation, feeling fat, elevated body mass, emotionality, and parental history of eating pathology predicted the future onset of eating-disordered behaviors extend past findings.</p>","PeriodicalId":20891,"journal":{"name":"Psychological Medicine","volume":"55 ","pages":"e48"},"PeriodicalIF":5.9000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychological Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/S0033291724003337","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: We conducted a prospective study to advance knowledge of biological factors that predict the future onset of binge eating and compensatory weight control behaviors because few biological risk factors for eating pathology have been identified.

Methods: Adolescent girls free of binge eating or compensatory behaviors (N = 88; Mage = 14.5; [SD = 0.9]) completed functional magnetic resonance imaging tasks assessing individual differences in neural responsivity hypothesized to increase risk for onset of binge eating and compensatory behaviors, along with additional self-report measures, and were assessed over a 4-year follow-up.

Results: Elevated responsivity of regions implicated in attention and valuation (dorsal anterior cingulate cortex; ventromedial prefrontal cortex) to thin models and lower responsivity of a reward valuation region (caudate) to anticipated milkshake tastes (which correlated with feeling fat) predicted the future onset of binge eating or compensatory behaviors over 4-year follow-up. Parental history of binge eating and compensatory behaviors, emotionality, weight/shape overvaluation, feeling fat, and elevated BMI also predicted the future onset of binge eating or compensatory behaviors.

Conclusions: The evidence that elevated attentional bias for, and valuation of the thin ideal, in combination with lower valuation of high-calorie foods, predicted the future onset of eating-disordered behaviors are novel findings. The evidence that weight/shape overvaluation, feeling fat, elevated body mass, emotionality, and parental history of eating pathology predicted the future onset of eating-disordered behaviors extend past findings.

预测未来暴饮暴食或代偿性体重控制行为的神经危险因素:一项为期4年的前瞻性fMRI研究
背景:我们进行了一项前瞻性研究,以提高对预测暴饮暴食和代偿性体重控制行为未来发病的生物学因素的认识,因为很少有饮食病理的生物学危险因素被确定。方法:无暴食或代偿行为的青春期少女(N = 88;法师= 14.5;[SD = 0.9])完成功能性磁共振成像任务,评估神经反应性的个体差异,假设会增加暴饮暴食和代偿行为发生的风险,以及额外的自我报告测量,并在4年的随访中进行评估。结果:与注意和评价有关的区域的反应性升高(前扣带回背;在4年的随访中,腹内侧前额叶皮层对瘦模型和奖励评估区域(尾状核)对预期奶昔口味(与感觉肥胖相关)的较低反应预测了未来暴饮暴食或代偿行为的发生。父母暴饮暴食和代偿行为的历史、情绪、体重/体型高估、感觉肥胖和BMI升高也可以预测未来暴饮暴食或代偿行为的发生。结论:有证据表明,对理想身材的注意偏差和评价的提高,以及对高热量食物的评价的降低,预示着未来饮食失调行为的发生,这是一个新的发现。体重/体型高估、感觉肥胖、体重增加、情绪和父母饮食病理史预测未来饮食失调行为的证据扩展了过去的发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Psychological Medicine
Psychological Medicine 医学-精神病学
CiteScore
11.30
自引率
4.30%
发文量
711
审稿时长
3-6 weeks
期刊介绍: Now in its fifth decade of publication, Psychological Medicine is a leading international journal in the fields of psychiatry, related aspects of psychology and basic sciences. From 2014, there are 16 issues a year, each featuring original articles reporting key research being undertaken worldwide, together with shorter editorials by distinguished scholars and an important book review section. The journal''s success is clearly demonstrated by a consistently high impact factor.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信