Relationship between accelerometer-measured physical activity and depressive symptoms in hemodialysis patients with comorbid diabetes mellitus: a multicenter cross-sectional study.
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引用次数: 0
Abstract
Objective: The objective of this study was to examine the association between accelerometer-derived moderate-to-vigorous physical activity (MVPA) and depressive symptoms in hemodialysis patients with and without type 2 diabetes mellitus (T2DM).
Methods: This cross-sectional study finally included 450 maintenance hemodialysis patients (male 281, average age 62 years) from seven dialysis centers in Shanghai, China. Physical activity (PA) was measured using the triaxial accelerometer (ActiGraph GT3X+, Pensacola, FL, United States). We measured depressive symptoms using the 9-item Patient Health Questionnaire (PHQ-9) (PHQ-9 ⩾ 10). We categorized physical activity into quartile groups (Q1 through Q4), with the first quartile defined as low engagement and the remaining quartiles defined as moderate to high engagement. We used logistic regression and trend test to analyze the relationship between quartile groups and depressive symptoms. The analyses in this study adjusted for a range of confounders.
Results: The prevalence of depression was higher in patients with hemodialysis combined with T2DM (17.2%). In diabetic patients, MVPAQ4 was negatively associated with depression after adjusting for covariates [OR = 0.076; 95% confidence interval (CI) = 0.006-0.955, p = 0.046]. However, in non-diabetic hemodialysis patients, no significant association was found between MVPAQ1-Q4 and depression after adjusting for covariates (p > 0.05).
Conclusion: Moderate-to-vigorous physical activity was associated with depression in the diabetic hemodialysis group, but not in the non-diabetic group. Further studies are needed to investigate more causal relationships between MVPA and depressive symptoms in patients with T2DM.
期刊介绍：
Frontiers in Psychology is the largest journal in its field, publishing rigorously peer-reviewed research across the psychological sciences, from clinical research to cognitive science, from perception to consciousness, from imaging studies to human factors, and from animal cognition to social psychology. Field Chief Editor Axel Cleeremans at the Free University of Brussels is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. The journal publishes the best research across the entire field of psychology. Today, psychological science is becoming increasingly important at all levels of society, from the treatment of clinical disorders to our basic understanding of how the mind works. It is highly interdisciplinary, borrowing questions from philosophy, methods from neuroscience and insights from clinical practice - all in the goal of furthering our grasp of human nature and society, as well as our ability to develop new intervention methods.
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