MRI biomarkers and their correlation with the Oncotype DX test

Abstract

Breast cancer (BC) has high rates of incidence and prevalence, causing significant impact in our society. Magnetic resonance imaging (MRI) plays a crucial role in its detection and staging. The Oncotype DX Breast Recurrence Score (ODXRS) test can be used to guide decision making regarding adjuvant chemotherapy (CT) in early-stage luminal BC to allow for more tailored cancer treatment. The aim of this article is to review knowledge regarding MRI biomarkers to date according to the BI-RADS® classification and the use of artificial intelligence (AI) in this imaging technique to establish its correlation with the ODXRS test. The latest studies published on AI and MRI present promising findings, and their standardisation could mark a turning point in breast radiology.