Future perspectives of fertility protection

IF 2.9 3区 医学 Q3 IMMUNOLOGY
Karin Bundschu , Silviya Aleksandrova-Yankulovska , Christian Denzer , Tana Dornbrach , Sabine Eberhart , Lazar Glisic , Ana Gomes Barata , Harald Gündel , Klaus Hönig , Wolfgang Janni , Karamdeep Khinda , Laura Rafensteiner , Reiner Siebert , Florian Steger , Stephan Stilgenbauer , Martin Wabitsch , Lisa Wiesmüller , Miriam Wilhelm , Birgit Wojak , Katharina Hancke
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引用次数: 0

Abstract

Reproductive health is of major importance for individuals, for the society and for the health of future generations. This includes physical and medical dimensions as well as psychosocial and ethical ones. Whenever the possibility of starting a family is compromised, either due to an oncological cytotoxic treatment or due to transgender hormone medication with the aim to align their secondary sexual characteristics or other medical or social conditions, one key aspect of reproductive health is fertility protection. However, as a very young field in medicine, there are still many research questions that need to be clarified to provide the best possible treatment for affected people. These include the optimization and safety of cryopreservation processes of germ cells in women, men, transgender people, adolescents and children. Another focus is on psychological care as well as ethical, economic and legal issues. The establishment and development of the center for fertility protection Ulm (FePro-Ulm) will focus on a detailed molecular biological and (epi)genetic understanding of the underlying processes in ovarian tissue, oocytes and sperm to improve and develop new diagnostic and therapeutic approaches. The individual needs of affected people, their partners and families will be evaluated by an interdisciplinary approach. The collaborations within FePro-Ulm will develop preventative and helpful interventions for affected people. In addition, a better awareness of this important topic of reproductive health and fertility protection will be addressed by including participation representatives and strengthen public relation works.
生育保护的未来展望
生殖健康对个人、社会和子孙后代的健康都具有重大意义。这包括身体和医疗方面以及社会心理和道德方面。无论何时,由于肿瘤细胞毒性治疗或为了调整第二性征或其他医疗或社会条件而使用跨性别激素药物,当建立家庭的可能性受到损害时,生殖健康的一个关键方面就是生育保护。然而,作为一个非常年轻的医学领域,仍有许多研究问题需要澄清,以便为受影响的人提供最好的治疗。其中包括女性、男性、变性人、青少年和儿童生殖细胞冷冻保存过程的优化和安全性。另一个重点是心理护理以及伦理、经济和法律问题。生育保护中心(FePro-Ulm)的建立和发展将专注于对卵巢组织、卵母细胞和精子的潜在过程进行详细的分子生物学和(epi)遗传学理解,以改进和开发新的诊断和治疗方法。将采用跨学科方法评估受影响者及其伴侣和家庭的个人需要。FePro-Ulm内部的合作将为受影响的人开发预防性和有益的干预措施。此外,将通过纳入参与代表和加强公共关系工作,提高对生殖健康和生育保护这一重要主题的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.30
自引率
5.90%
发文量
162
审稿时长
10.6 weeks
期刊介绍: Affiliated with the European Society of Reproductive Immunology and with the International Society for Immunology of Reproduction The aim of the Journal of Reproductive Immunology is to provide the critical forum for the dissemination of results from high quality research in all aspects of experimental, animal and clinical reproductive immunobiology. This encompasses normal and pathological processes of: * Male and Female Reproductive Tracts * Gametogenesis and Embryogenesis * Implantation and Placental Development * Gestation and Parturition * Mammary Gland and Lactation.
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