Karin Bundschu , Silviya Aleksandrova-Yankulovska , Christian Denzer , Tana Dornbrach , Sabine Eberhart , Lazar Glisic , Ana Gomes Barata , Harald Gündel , Klaus Hönig , Wolfgang Janni , Karamdeep Khinda , Laura Rafensteiner , Reiner Siebert , Florian Steger , Stephan Stilgenbauer , Martin Wabitsch , Lisa Wiesmüller , Miriam Wilhelm , Birgit Wojak , Katharina Hancke
{"title":"Future perspectives of fertility protection","authors":"Karin Bundschu , Silviya Aleksandrova-Yankulovska , Christian Denzer , Tana Dornbrach , Sabine Eberhart , Lazar Glisic , Ana Gomes Barata , Harald Gündel , Klaus Hönig , Wolfgang Janni , Karamdeep Khinda , Laura Rafensteiner , Reiner Siebert , Florian Steger , Stephan Stilgenbauer , Martin Wabitsch , Lisa Wiesmüller , Miriam Wilhelm , Birgit Wojak , Katharina Hancke","doi":"10.1016/j.jri.2025.104455","DOIUrl":null,"url":null,"abstract":"<div><div>Reproductive health is of major importance for individuals, for the society and for the health of future generations. This includes physical and medical dimensions as well as psychosocial and ethical ones. Whenever the possibility of starting a family is compromised, either due to an oncological cytotoxic treatment or due to transgender hormone medication with the aim to align their secondary sexual characteristics or other medical or social conditions, one key aspect of reproductive health is fertility protection. However, as a very young field in medicine, there are still many research questions that need to be clarified to provide the best possible treatment for affected people. These include the optimization and safety of cryopreservation processes of germ cells in women, men, transgender people, adolescents and children. Another focus is on psychological care as well as ethical, economic and legal issues. The establishment and development of the center for fertility protection Ulm (<strong>FePro-Ulm</strong>) will focus on a detailed molecular biological and (epi)genetic understanding of the underlying processes in ovarian tissue, oocytes and sperm to improve and develop new diagnostic and therapeutic approaches. The individual needs of affected people, their partners and families will be evaluated by an interdisciplinary approach. The collaborations within FePro-Ulm will develop preventative and helpful interventions for affected people. In addition, a better awareness of this important topic of reproductive health and fertility protection will be addressed by including participation representatives and strengthen public relation works.</div></div>","PeriodicalId":16963,"journal":{"name":"Journal of Reproductive Immunology","volume":"168 ","pages":"Article 104455"},"PeriodicalIF":2.9000,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Reproductive Immunology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165037825000336","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Reproductive health is of major importance for individuals, for the society and for the health of future generations. This includes physical and medical dimensions as well as psychosocial and ethical ones. Whenever the possibility of starting a family is compromised, either due to an oncological cytotoxic treatment or due to transgender hormone medication with the aim to align their secondary sexual characteristics or other medical or social conditions, one key aspect of reproductive health is fertility protection. However, as a very young field in medicine, there are still many research questions that need to be clarified to provide the best possible treatment for affected people. These include the optimization and safety of cryopreservation processes of germ cells in women, men, transgender people, adolescents and children. Another focus is on psychological care as well as ethical, economic and legal issues. The establishment and development of the center for fertility protection Ulm (FePro-Ulm) will focus on a detailed molecular biological and (epi)genetic understanding of the underlying processes in ovarian tissue, oocytes and sperm to improve and develop new diagnostic and therapeutic approaches. The individual needs of affected people, their partners and families will be evaluated by an interdisciplinary approach. The collaborations within FePro-Ulm will develop preventative and helpful interventions for affected people. In addition, a better awareness of this important topic of reproductive health and fertility protection will be addressed by including participation representatives and strengthen public relation works.
期刊介绍:
Affiliated with the European Society of Reproductive Immunology and with the International Society for Immunology of Reproduction
The aim of the Journal of Reproductive Immunology is to provide the critical forum for the dissemination of results from high quality research in all aspects of experimental, animal and clinical reproductive immunobiology.
This encompasses normal and pathological processes of:
* Male and Female Reproductive Tracts
* Gametogenesis and Embryogenesis
* Implantation and Placental Development
* Gestation and Parturition
* Mammary Gland and Lactation.