Boron neutron capture therapy (BNCT) for left axillary lymph node metastasis of recurrent breast cancer

IF 1.6 3区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR

Applied Radiation and Isotopes Pub Date : 2025-02-10 DOI:10.1016/j.apradiso.2025.111715

Takuya Fujimoto , Yoko Maekawa , Shinichi Hori , Atsushi Oguro , Atsushi Hori , Ikuo Fujita , Yoshinori Sakurai , Hiroki Tanaka , Tatsuya Ito , Shunsuke Yahiro , Toshiko Sakuma , Minoru Suzuki

引用次数: 0

Abstract

Here described for the first time is the efficacy of p-boronophenylalanine (BPA)-based BNCT in the clinical treatment of metastatic breast cancer. The patient was diagnosed with left axillary lymph node metastasis from breast cancer with comorbidity of neuropathy. Although several treatment strategies for suppressing the progression of the cancer were unavailing, BPA-based BNCT impeded the progression. This clinical case suggests the applicability of this new method of treatment to not only metastatic but also primary breast cancer.

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来源期刊

Applied Radiation and Isotopes 工程技术-核科学技术

CiteScore

3.00

自引率

12.50%

发文量

406

审稿时长

13.5 months

期刊介绍： Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.