Evaluation of wear, corrosion, and biocompatibility of a novel biomedical TiZr-based medium entropy alloy

IF 3.3 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-02-13 DOI:10.1016/j.jmbbm.2025.106951

Dandan Zhu , Xiaoqiang Li , Shaoyu Chai , Tien-Shee Chee , Chaerin Kim , Liang Li , Dexue Liu

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引用次数: 0

Abstract

As a promising material for medical implants, the Ti₄₀Zr₄₀Nb₅Ta₁₂Sn₃ medium entropy alloy (MEA) shows potential for biomedical applications. This study investigates its wear and corrosion behavior in simulated biological environments, including artificial saliva (AS), simulated blood (SB), and simulated body fluid (SBF). Electrochemical tests revealed excellent corrosion resistance in AS solution, with a higher corrosion potential (−0.31420 V) and a lower corrosion current density (2.613 × 10⁻⁷ A·cm⁻²). Wear tests showed that friction coefficients ranked as μ_AS > μ_SBF > μ_SB, while wear rates followed δ_SBF > δ_SB > δ_AS, highlighting the impact of bio-lubricants composition on tribological behavior. In particular, the alloy exhibited a higher ion release rate in the SBF solution, with ion concentrations approximately 2.5 times greater than those in the AS solution. In contrast, the alloy in the AS solution maintained a more stable passivation film, thus reducing ion release and enhancing both wear and corrosion resistance of the alloy. The biocompatibility test further confirmed that it has good cell adhesion and proliferation ability. This study provides valuable insights into the synergistic effects of wear and corrosion on the alloy in simulated physiological environments.

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一种新型生物医用tizr基中熵合金的磨损、腐蚀和生物相容性评估

Ti40Zr40Nb5Ta12Sn3中熵合金（MEA）是一种很有前途的医用植入材料，在生物医学领域具有广阔的应用前景。研究了其在人工唾液（AS）、模拟血液（SB）和模拟体液（SBF）等模拟生物环境中的磨损和腐蚀行为。电化学测试表明，在AS溶液中具有优异的耐腐蚀性，具有较高的腐蚀电位（−0.31420 V）和较低的腐蚀电流密度（2.613 × 10⁻a·cm⁻2）。磨损试验表明，摩擦系数为μAS >；μSBF祝辞μSB，磨损率δSBF >；δ某人比;δAS，强调了生物润滑油成分对摩擦学行为的影响。特别是，合金在SBF溶液中离子释放速率更高，离子浓度约为AS溶液的2.5倍。相比之下，合金在AS溶液中保持了更稳定的钝化膜，从而减少了离子释放，提高了合金的耐磨损和耐腐蚀性能。生物相容性试验进一步证实其具有良好的细胞粘附和增殖能力。该研究为模拟生理环境下合金的磨损和腐蚀协同效应提供了有价值的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.