Cognitive impairment in patients with heart failure: Physiopathology, clinical implications, and therapeutic considerations.

IF 2.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Meng Li, Junping Zhang, Yue Hu, Yue Zhang
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引用次数: 0

Abstract

Cognitive impairment (CI) is a significant comorbidity in individuals with heart failure (HF). A substantial number of patients with HF may experience CI, which can present as deficits in attention, memory, executive function, and processing speed. HF patients with CI tend to have reduced functional independence, self-care capabilities, medication adherence and decision-making ability, along with more frequent rehospitalizations, and an increased risk of mortality. Currently, there is no established gold standard diagnostic tool or follow-up strategy for assessing CI in patients with HF. There has been an increasing recognition of the complex bidirectional relationship between HF and CI. However, the exact pathological mechanisms of CI in HF need further in-depth investigation. This review aims to explore the current epidemiological status of CI in patients with HF, the relationship between HF and cognitive dysfunction, the pathological mechanisms involved, as well as the early screening, diagnosis, and management issues for HF patients with CI. It also discusses prevention and intervention strategies. The objective is to provide a scientific basis for the clinical diagnosis, management, and treatment of CI in HF, while proposing future research directions to advance this field.

心力衰竭患者的认知障碍:生理病理、临床意义和治疗考虑。
认知障碍(CI)是心力衰竭(HF)患者的重要合并症。大量心衰患者可能经历CI,表现为注意力、记忆、执行功能和处理速度的缺陷。合并CI的心衰患者往往功能独立性、自我护理能力、药物依从性和决策能力较低,再住院频率更高,死亡风险增加。目前,还没有确定的金标准诊断工具或随访策略来评估心衰患者的CI。人们越来越认识到HF和CI之间复杂的双向关系。然而,心衰CI的确切病理机制有待进一步深入研究。本文旨在探讨HF合并CI患者的流行病学现状、HF与认知功能障碍的关系、相关病理机制以及HF合并CI患者的早期筛查、诊断和处理问题。它还讨论了预防和干预策略。目的是为心衰CI的临床诊断、管理和治疗提供科学依据,同时提出未来的研究方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of cardiology
Journal of cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.90
自引率
8.00%
发文量
202
审稿时长
29 days
期刊介绍: The official journal of the Japanese College of Cardiology is an international, English language, peer-reviewed journal publishing the latest findings in cardiovascular medicine. Journal of Cardiology (JC) aims to publish the highest-quality material covering original basic and clinical research on all aspects of cardiovascular disease. Topics covered include ischemic heart disease, cardiomyopathy, valvular heart disease, vascular disease, hypertension, arrhythmia, congenital heart disease, pharmacological and non-pharmacological treatment, new diagnostic techniques, and cardiovascular imaging. JC also publishes a selection of review articles, clinical trials, short communications, and important messages and letters to the editor.
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