Milling-based extraction and characterization of Bombyx mori silk glands and fibroin powder for biomaterial use

IF 4.2 2区工程技术 Q2 ENGINEERING, CHEMICAL

Advanced Powder Technology Pub Date : 2025-02-16 DOI:10.1016/j.apt.2025.104820

Norihiro Yoshida , Mayumi Tsukada , Masayuki Horio , Akio Nonaka , Akira Nonaka , I. Wuled Lenggoro

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引用次数: 0

Abstract

This study presents an approach for the extraction of silk glands from Bombyx mori silkworms using a scalable wet milling process, eliminating the need for traditional cocoon processing. We developed a method to harvest silk glands, followed by dry-milling to generate fibroin powders. This technique allows for on-demand extraction by storing silkworms in ethanol aqueous systems or freeze conditions. We systematically investigated the influence of ethanol and freeze-pretreatments on the properties of the extracted silk materials. Ethanol-pretreatment was found to decrease the hardness of silk glands after degumming, while freeze-pretreatment enhanced hardness and introduced a porous structure. Additionally, freeze-pretreated silk powders exhibited larger particle sizes and higher crystallinity compared to those treated with ethanol. These findings highlight the potential of using silk glands as sustainable alternatives to plastics and open new avenues for advanced biomaterial applications.

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来源期刊

Advanced Powder Technology 工程技术-工程：化工

CiteScore

9.50

自引率

7.70%

发文量

424

审稿时长

55 days

期刊介绍： The aim of Advanced Powder Technology is to meet the demand for an international journal that integrates all aspects of science and technology research on powder and particulate materials. The journal fulfills this purpose by publishing original research papers, rapid communications, reviews, and translated articles by prominent researchers worldwide. The editorial work of Advanced Powder Technology, which was founded as the International Journal of the Society of Powder Technology, Japan, is now shared by distinguished board members, who operate in a unique framework designed to respond to the increasing global demand for articles on not only powder and particles, but also on various materials produced from them. Advanced Powder Technology covers various areas, but a discussion of powder and particles is required in articles. Topics include: Production of powder and particulate materials in gases and liquids(nanoparticles, fine ceramics, pharmaceuticals, novel functional materials, etc.); Aerosol and colloidal processing; Powder and particle characterization; Dynamics and phenomena; Calculation and simulation (CFD, DEM, Monte Carlo method, population balance, etc.); Measurement and control of powder processes; Particle modification; Comminution; Powder handling and operations (storage, transport, granulation, separation, fluidization, etc.)