Antibacterial and bactericidal properties of resin nanostructures coated with SiO2 thin films

IF 5.4 2区医学 Q1 BIOPHYSICS

Colloids and Surfaces B: Biointerfaces Pub Date : 2025-02-11 DOI:10.1016/j.colsurfb.2025.114560

Yuito Matsushita , Gakuto Inoue , Zihao Zhao , Natsuki Ogawa , Hitoshi Ishiguro , Kayano Sunada , Kenta Ishibashi , Hiroaki Kojima , Tomohiro Shimizu , Shoso Shingubara , Takeshi Ito

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引用次数: 0

Abstract

Nanotextures exhibit physical antibacterial and bactericidal properties; hence, they have great potential to prevent infection related to bacteria through contact. The surface characteristics of a nanostructure determine its antibacterial and bactericidal activities. In this study, an atomic layer deposition (ALD) was used to prepare nano-level, hard, thin SiO₂ layers on resin nanostructures and their effects were demonstrated through antibacterial and bactericidal tests. The SiO₂-layer-coated resin nanostructure exhibited a water contact angle of 7.2°, dramatically lower than that of the uncoated specimen (130.2°), as well as a three-fold higher local elastic modulus. Further, 10-nm-thin SiO₂-layer-coated nanopillars showed antibacterial and bactericidal effects against E. coli. These results demonstrate that SiO₂ thin layer coating has great potential for improving the antibacterial and bactericidal properties of polymeric nanopillar arrays.

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来源期刊

Colloids and Surfaces B: Biointerfaces 生物-材料科学：生物材料

CiteScore

11.10

自引率

3.40%

发文量

730

审稿时长

42 days

期刊介绍： Colloids and Surfaces B: Biointerfaces is an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, having particular relevance to the medical, pharmaceutical, biotechnological, food and cosmetic fields. Submissions that: (1) deal solely with biological phenomena and do not describe the physico-chemical or colloid-chemical background and/or mechanism of the phenomena, and (2) deal solely with colloid/interfacial phenomena and do not have appropriate biological content or relevance, are outside the scope of the journal and will not be considered for publication. The journal publishes regular research papers, reviews, short communications and invited perspective articles, called BioInterface Perspectives. The BioInterface Perspective provide researchers the opportunity to review their own work, as well as provide insight into the work of others that inspired and influenced the author. Regular articles should have a maximum total length of 6,000 words. In addition, a (combined) maximum of 8 normal-sized figures and/or tables is allowed (so for instance 3 tables and 5 figures). For multiple-panel figures each set of two panels equates to one figure. Short communications should not exceed half of the above. It is required to give on the article cover page a short statistical summary of the article listing the total number of words and tables/figures.