Sequential Knee and Hip Arthroplasty in a Patient With Pfeifer-Weber-Christian Disease

IF 1.5 Q3 ORTHOPEDICS

Arthroplasty Today Pub Date : 2025-02-17 DOI:10.1016/j.artd.2025.101637

Edgar Barros Prieto MD , Eduardo Noboa Freile MD , Carlos Peñaherrera Carillo MD , Francisco Endara Urresta MD , Alejandro Barros Castro MD , Paul Vaca Perez MD

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引用次数: 0

Abstract

Pfeifer-Weber-Christian Disease (PWCD) is a rare chronic inflammatory condition characterized by recurrent painful subcutaneous nodules and systemic manifestations. Long-term corticosteroid therapy, essential for managing PWCD, predisposes patients to complications such as osteoarthritis and avascular necrosis, often necessitating joint replacement surgeries. This report discusses a 38-year-old woman with a 15-year history of PWCD who underwent sequential knee and hip arthroplasty due to severe joint degeneration. The patient presented with debilitating pain, significant functional impairment, and advanced degenerative changes in the left knee and right hip. A multidisciplinary team provided comprehensive perioperative care to address the complexities of chronic inflammation, immunosuppression, and poor bone quality. This case highlights the feasibility of joint replacement in PWCD patients when a multidisciplinary approach and meticulous planning are applied. It underscores the importance of individualized surgical strategies and extended follow-up to optimize outcomes in complex cases.

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来源期刊

Arthroplasty Today Medicine-Surgery

CiteScore

2.90

自引率

0.00%

发文量

258

审稿时长

40 weeks

期刊介绍： Arthroplasty Today is a companion journal to the Journal of Arthroplasty. The journal Arthroplasty Today brings together the clinical and scientific foundations for joint replacement of the hip and knee in an open-access, online format. Arthroplasty Today solicits manuscripts of the highest quality from all areas of scientific endeavor that relate to joint replacement or the treatment of its complications, including those dealing with patient outcomes, economic and policy issues, prosthetic design, biomechanics, biomaterials, and biologic response to arthroplasty. The journal focuses on case reports. It is the purpose of Arthroplasty Today to present material to practicing orthopaedic surgeons that will keep them abreast of developments in the field, prove useful in the care of patients, and aid in understanding the scientific foundation of this subspecialty area of joint replacement. The international members of the Editorial Board provide a worldwide perspective for the journal''s area of interest. Their participation ensures that each issue of Arthroplasty Today provides the reader with timely, peer-reviewed articles of the highest quality.