Visible light-induced radical cascade hydroaminoalkylation involving two distinct alkenes

IF 6.5 1区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Catalysis Pub Date : 2025-02-14 DOI:10.1016/j.jcat.2025.116010

Zhu-Ming Qian , Qin Zhang , Ya-Nan Zhao , Zhi Guan , Chu-Sheng Huang , Yan-Hong He

引用次数: 0

Abstract

This paper describes a visible-light-mediated three-component dicarbofunctionalization of alkenes via a tandem radical addition reaction of two different alkenes triggered by aminoalkyl radicals derived from N-phenyl glycines. This method allows for one-pot skeletal assembly, providing efficient and straightforward access to structurally complex γ-amino sulfone derivatives directly from readily available and simple starting materials. Beyond the convenience of the one-pot protocol, this method also demonstrates broad substrate scope, excellent functional group compatibility, mild reaction conditions, and ease of scalability.

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涉及两种不同烯烃的可见光诱导自由基级联氢氨烷基化反应

本文介绍了一种可见光介导的烯烃三组分二羧官能化方法，该方法是由 N-苯基甘氨酸衍生的氨基烷基引发两种不同烯烃的串联自由基加成反应。这种方法可以实现单锅骨架组装，直接从容易获得的简单起始材料中高效、直接地获得结构复杂的 γ-氨基砜衍生物。除了单锅方案的便利性之外，该方法还展示了广泛的底物范围、优异的官能团兼容性、温和的反应条件和易于扩展性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Catalysis 工程技术-工程：化工

CiteScore

12.30

自引率

5.50%

发文量

447

审稿时长

31 days

期刊介绍： The Journal of Catalysis publishes scholarly articles on both heterogeneous and homogeneous catalysis, covering a wide range of chemical transformations. These include various types of catalysis, such as those mediated by photons, plasmons, and electrons. The focus of the studies is to understand the relationship between catalytic function and the underlying chemical properties of surfaces and metal complexes. The articles in the journal offer innovative concepts and explore the synthesis and kinetics of inorganic solids and homogeneous complexes. Furthermore, they discuss spectroscopic techniques for characterizing catalysts, investigate the interaction of probes and reacting species with catalysts, and employ theoretical methods. The research presented in the journal should have direct relevance to the field of catalytic processes, addressing either fundamental aspects or applications of catalysis.