The relationship between anxiety, depression, and COVID-19 diagnosis in term pregnancy: a hospital-based Romanian study.

Q2 Medicine
Medicine and Pharmacy Reports Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI:10.15386/mpr-2799
Gabriela Caracostea, Elisabeta Ioana Hirişcău, Andreia Paraschiva Preda, Teodora Turta, Lavinia Argentina Ionescu, Izabela Ramona Lupu, Mihai Surcel, Monica Mihaela Marta, Viorel Lupu, Silviu Matu
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Abstract

Background and aim: There are few published data on the mental health problems of women with pregnancy complicated by SARS-CoV-2 infection. Our study aimed to evaluate anxiety and depression related to a COVID-19 diagnosis in women who gave birth in a Romanian tertiary maternity.

Methods: A hospital-based cross-sectional study was conducted between September 2020 and October 2021 on 105 women admitted for term delivery; 51 women were diagnosed with SARS-CoV-2 infection just before delivery, and 54 without infection. Participants were assessed during the first 72 hours postpartum (T1) and the following two weeks postpartum (T2). Hospital Anxiety and Depression Scale (HADS) was used for anxiety and depression assessment at T1. The COVID-19 Pandemic Mental Health Questionnaire (CoPaQ) was applied at T2 only in the COVID-positive cases identified at T1.

Results: Postnatal anxiety levels were higher in COVID-positive women compared to COVID-negative women (p = .004), but there were no differences in the postnatal depression level between the groups. Psychological manifestations related to the pandemic, such as contamination anxiety, posttraumatic stress disorder (PTSD), and obsessive-compulsive disorder (OCD) symptoms, were positively related to HADS anxiety scores, while maintaining social relationships were negatively associated with the scale. The COVID-19 diagnosis was found to be a significant predictor for adverse pregnancy outcomes (APOs), with COVID-positive women having a 4.72-fold higher risk of developing them than those who tested COVID-negative (OR=4.72, 95% CI [2.05; 10.86]). The multivariate analysis using anxiety and depression as dependent variables indicated a significant effect for COVID-19 diagnosis, Wilks' Lambda = 0.940, p = 0.048.

Conclusion: Increased levels of anxiety, PTSD, and obsessive-compulsive symptoms were associated with the postpartum period in pregnant women with COVID-19 infection during delivery. Maintaining social interaction proved to be a protective factor against the increased anxiety reported by COVID-19-infected women.

焦虑、抑郁和足月妊娠COVID-19诊断之间的关系:一项基于医院的罗马尼亚研究
背景与目的:关于妊娠合并SARS-CoV-2感染的女性心理健康问题的公开数据很少。我们的研究旨在评估在罗马尼亚第三产科分娩的妇女中与COVID-19诊断相关的焦虑和抑郁。方法:在2020年9月至2021年10月期间,对105名足月分娩的妇女进行了一项基于医院的横断面研究;51名妇女在分娩前被诊断为SARS-CoV-2感染,54名未被感染。参与者在产后72小时(T1)和产后两周(T2)进行评估。T1时采用医院焦虑抑郁量表(HADS)进行焦虑抑郁评估。T2时仅对T1时发现的COVID-19阳性病例使用COVID-19大流行心理健康问卷(CoPaQ)。结果:新冠病毒阳性妇女产后焦虑水平高于新冠病毒阴性妇女(p = 0.004),但两组间产后抑郁水平无差异。与大流行相关的心理表现,如污染焦虑、创伤后应激障碍(PTSD)和强迫症(OCD)症状,与HADS焦虑得分呈正相关,而维持社会关系与量表负相关。发现COVID-19诊断是不良妊娠结局(APOs)的重要预测因子,COVID-19阳性妇女发生不良妊娠结局(APOs)的风险比COVID-19阴性妇女高4.72倍(OR=4.72, 95% CI [2.05;10.86])。以焦虑和抑郁为因变量的多变量分析显示,焦虑和抑郁对COVID-19诊断有显著影响,Wilks’Lambda = 0.940, p = 0.048。结论:分娩期间感染COVID-19的孕妇的焦虑、PTSD和强迫症水平升高与产后有关。事实证明,保持社交互动是防止感染covid -19的妇女报告的焦虑加剧的一个保护因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medicine and Pharmacy Reports
Medicine and Pharmacy Reports Medicine-Medicine (all)
CiteScore
3.10
自引率
0.00%
发文量
63
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