Origanum Essential Oil and Antifungal Activity: A Systematic Review.

IF 2.3 3区化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Chemistry & Biodiversity Pub Date : 2025-02-13 DOI:10.1002/cbdv.202402296

Leticia Mezzomo, Juliana Butzge, Mariana Fiorio, Caroline Bastian, Adelina Mezzari, Alexandre Fuentefria, Miriam Anders Apel

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引用次数: 0

Abstract

Fungi are pathogens that affect humans, animals, food and plants. Many strains are resistant to currently available antifungals, which are also associated with high toxicity and can cause environmental pollution. Treatments are lengthy with low adherence rates. Given plant´s historical use in disease treatment, natural products, such as essential oils,have been studied and developed for fungal infection treatment. Therefore, the aim of this study was to conduct a systematic literature review on Origanum species commercialized in Brazil: Origanum compactum, O. minutiflorum, O. syriacum, and O. vulgare, focusing on the chemical composition of their oils and their antifungal activity. A systematic literature review was conducted following PRISMA guidelines, using the databases ScienceDirect, Scielo, PubMed, Scopus, and Web of Science. O. vulgare presented the highest number of articles, and O. compactum showed the best results in terms of MIC and against the evaluated fungal species. Candida spp., Aspergillus spp., and Penicillium spp. were the most studied fungi. Carvacrol, thymol, p-cymene, o-cymene, and γ-terpinene are key constituents linked to their antifungal effects. The findings of this review highlight the chemical diversity of the studied genera and underscore the potential of Origanum spp.essential oils as antifungal agents against a variety of fungi.

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来源期刊

Chemistry & Biodiversity 环境科学-化学综合

CiteScore

3.40

自引率

10.30%

发文量

475

审稿时长

2.6 months

期刊介绍： Chemistry & Biodiversity serves as a high-quality publishing forum covering a wide range of biorelevant topics for a truly international audience. This journal publishes both field-specific and interdisciplinary contributions on all aspects of biologically relevant chemistry research in the form of full-length original papers, short communications, invited reviews, and commentaries. It covers all research fields straddling the border between the chemical and biological sciences, with the ultimate goal of broadening our understanding of how nature works at a molecular level. Since 2017, Chemistry & Biodiversity is published in an online-only format.