Therapeutic Applications of Hair Follicle Transplantation Beyond Hair Restoration.

IF 2.5 3区医学 Q2 DERMATOLOGY

Dermatologic Surgery Pub Date : 2025-02-14 DOI:10.1097/DSS.0000000000004571

Rimma Laufer-Britva, Wipawan Vathananai, Francisco Jimenez

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引用次数: 0

Abstract

Background: Hair follicle (HF) transplantation, especially through follicular unit excision (FUE), is renowned for treating androgenetic alopecia. Recent advancements have expanded its use in dermatology and plastic surgery.

Objective: This review explores FUE's broader applications beyond hair restoration, including its efficacy in treating chronic ulcers, axillary hyperhidrosis, bromhidrosis, vitiligo, and scar remodeling.

Methods: A comprehensive literature review was conducted using key medical databases, focusing on clinical research such as randomized controlled trials, retrospective studies, case series, and reports, while excluding review articles and commentaries.

Results: Hair follicle transplantation using the FUE technique has shown significant promise in enhancing healing in chronic ulcers and difficult to heal wounds, with cases demonstrating complete wound healing across various ulcer types. The method of sweat gland removal using FUE micropunches substantially reduced sweating and malodor in patients with axillary hyperhidrosis and bromhidrosis. In vitiligo treatment, FUE combined with other therapies showed promising repigmentation results.

Conclusion: Follicular unit excision emerges as a versatile surgical technique demonstrating potential in various conditions beyond alopecia. The minimal complications associated with FUE across various applications highlight its safety profile. Its expanding scope in medical applications calls for further research and clinical trials to optimize its use and understand its full therapeutic potential.

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来源期刊

Dermatologic Surgery 医学-皮肤病学

CiteScore

3.10

自引率

16.70%

发文量

547

期刊介绍： Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.