The impact of regular sauerkraut consumption on the human gut microbiota: a crossover intervention trial.

IF 13.8 1区生物学 Q1 MICROBIOLOGY

Microbiome Pub Date : 2025-02-12 DOI:10.1186/s40168-024-02016-3

Nelly Schropp, Alexander Bauer, Virginie Stanislas, Kun D Huang, Till-Robin Lesker, Agata Anna Bielecka, Till Strowig, Karin B Michels

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引用次数: 0

Abstract

Background: Sauerkraut is a fermented food that has been suspected to have a beneficial impact on the gut microbiome, but scientific evidence is sparse. In this crossover intervention trial with 87 participants (DRKS00027007), we investigated the impact of daily consumption of fresh or pasteurized sauerkraut for 4 weeks on gut microbial composition and the metabolome in a healthy study population.

Results: Using shotgun metagenomic sequencing, we observed changes in single bacterial species following fresh and pasteurized sauerkraut consumption. More pronounced changes were observed in the pasteurized sauerkraut intervention arm. Only pasteurized sauerkraut consumption increased serum short-chain fatty acids (SCFAs).

Conclusions: The gut microbiome of healthy individuals is rather resilient to short-term dietary interventions even though single species might be affected by sauerkraut consumption. Video Abstract.

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经常食用酸菜对人体肠道微生物群的影响：一项交叉干预试验。

背景：酸菜是一种发酵食品，一直被怀疑对肠道微生物群有有益的影响，但科学证据很少。在这项有87名参与者（DRKS00027007）的交叉干预试验中，我们研究了在健康研究人群中连续4周每天食用新鲜酸菜或巴氏杀菌酸菜对肠道微生物组成和代谢组的影响。结果：使用散弹枪宏基因组测序，我们观察了新鲜和巴氏灭菌的酸菜食用后单一细菌种类的变化。在巴氏灭菌的酸菜干预组中观察到更明显的变化。只有食用巴氏杀菌的酸菜才会增加血清短链脂肪酸（SCFAs）。结论：健康个体的肠道微生物组对短期饮食干预具有相当的弹性，即使单一物种可能受到酸菜消费的影响。视频摘要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Microbiome MICROBIOLOGY-

CiteScore

21.90

自引率

2.60%

发文量

198

审稿时长

4 weeks

期刊介绍： Microbiome is a journal that focuses on studies of microbiomes in humans, animals, plants, and the environment. It covers both natural and manipulated microbiomes, such as those in agriculture. The journal is interested in research that uses meta-omics approaches or novel bioinformatics tools and emphasizes the community/host interaction and structure-function relationship within the microbiome. Studies that go beyond descriptive omics surveys and include experimental or theoretical approaches will be considered for publication. The journal also encourages research that establishes cause and effect relationships and supports proposed microbiome functions. However, studies of individual microbial isolates/species without exploring their impact on the host or the complex microbiome structures and functions will not be considered for publication. Microbiome is indexed in BIOSIS, Current Contents, DOAJ, Embase, MEDLINE, PubMed, PubMed Central, and Science Citations Index Expanded.