Impacts of Excessive Iron Intake on Infant Growth and Fluorimetric and Colorimetric Detection Methods: A Comprehensive Review.

IF 2.6 4区化学 Q2 BIOCHEMICAL RESEARCH METHODS

Journal of Fluorescence Pub Date : 2025-02-13 DOI:10.1007/s10895-025-04183-4

Alaa Shafie, Amal Adnan Ashour, Faris J Tayeb, Mohammed Fareed Felemban

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引用次数: 0

Abstract

Iron is an essential nutrient involved in various physiological processes, including oxygen transport, enzyme activity, and cellular metabolism. However, excessive iron accumulation in the body can disrupt this delicate balance, leading to adverse effects on growth and development. Maintaining optimal iron levels is crucial for pediatric health, as both deficiency and overload pose significant risks. Fluorometric and colorimetric sensing techniques play a vital role in accurately detecting Fe²⁺/Fe³⁺ levels in biological matrices, facilitating early diagnosis and intervention in cases of iron overload. This study explores the impact of excess iron on children growth parameters, offering insights that can inform public health policies and clinical strategies for promoting healthy development. Additionally, this review highlights recent advancements (2022-2024) in organic colorimetric and fluorometric probes, which exhibit high sensitivity and selectivity for Fe²⁺/Fe³⁺ detection at trace levels.

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来源期刊

Journal of Fluorescence 化学-分析化学

CiteScore

4.60

自引率

7.40%

发文量

203

审稿时长

5.4 months

期刊介绍： Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.