Comparison of heroin and fentanyl use in US nationally representative surveys.

IF 3.2 2区 医学 Q1 SUBSTANCE ABUSE
Jarratt D Pytell, Paul J Christine, Katherine LeMasters, Karilynn M Rockhill, Joshua C Black, Richard C Dart, Ingrid A Binswanger
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引用次数: 0

Abstract

Background: Given the opioid overdose crisis, surveillance of evolving opioid use patterns is critical to the effective deployment of mitigation strategies. The National Survey on Drug Use and Health (NSDUH) provided the first annual US estimate of illicitly manufactured fentanyl (IMF) use in 2022. However, as a household survey, NSDUH may not capture the full extent of population heroin and IMF use. We compare estimates of past-year heroin and IMF use and correlates of use in NSDUH and the Survey of Non-Medical Use of Prescription Drugs (NMURx) survey which employ an alternate sampling strategy.

Methods: We conducted a cross-sectional analysis of the 2022 NSDUH and NMURx. NSDUH samples respondents using a probability-based approach targeting community-dwelling individuals, while NMURx samples respondents using an opt-in, online survey panel. US adults ages 18 years and older were included. The main outcomes were differences in the weighted percentage of population reporting past-year use of heroin, IMF, and either heroin or IMF between the surveys. Secondary outcomes were the patterns of association of past-year heroin or IMF use with comorbid substance use, treatment utilization, and demographic characteristics between the surveys. Data were analyzed March to June 2024.

Results: NSDUH (n = 47,100 respondents) had a lower proportion of respondents who identified as non-Hispanic White and graduated college, and a higher proportion with past week employment than NMURx (N = 59,041 respondents). Past-year use of heroin, IMF, and either heroin or IMF were lower in the NSDUH than the NMURx. NSDUH estimated 0.52% (95% CI: 0.40%, 0.69%) %) of the US population used either heroin or IMF in the past year compared to 1.05% (95% CI: 0.97%, 1.14 0) in NMURx. In regression models, stimulant and benzodiazepine use were consistently associated with increased heroin or IMF use across both surveys.

Conclusions and relevance: The estimated prevalence of heroin or IMF use was nearly 50% higher in the NMURx compared to NSDUH. These results highlight the importance of using complementary surveillance approaches to obtain accurate estimates of the prevalence and patterns of heroin or IMF use.

Abstract Image

Abstract Image

美国全国代表性调查中海洛因和芬太尼使用情况的比较。
背景:鉴于阿片类药物过量危机,监测阿片类药物使用模式的演变对于有效部署缓解战略至关重要。国家药物使用和健康调查(NSDUH)提供了2022年美国非法制造芬太尼(IMF)使用的首次年度估计。然而,作为一项家庭调查,NSDUH可能无法全面反映人口海洛因和货币基金组织的使用情况。我们比较了过去一年海洛因和国际货币基金组织使用的估计以及NSDUH中使用的相关因素和采用替代抽样策略的处方药非医疗使用调查(NMURx)调查。方法:我们对2022年NSDUH和NMURx进行了横断面分析。NSDUH使用基于概率的方法对社区居民进行抽样调查,而NMURx使用可选择的在线调查小组对受访者进行抽样调查。研究对象包括18岁及以上的美国成年人。主要结果是两次调查之间报告过去一年使用海洛因、国际货币基金组织以及海洛因或国际货币基金组织的人口加权百分比的差异。次要结果是过去一年海洛因或IMF使用与共病物质使用、治疗利用和调查之间的人口统计学特征的关联模式。数据分析于2024年3月至6月进行。结果:NSDUH (n = 47,100名受访者)的非西班牙裔白人和大学毕业的受访者比例低于NMURx (n = 59,041名受访者),而上周就业的受访者比例更高。NSDUH组过去一年使用海洛因、IMF、海洛因或IMF的比例低于NMURx组。NSDUH估计,在过去一年中,美国人口中有0.52% (95% CI: 0.40%, 0.69%)使用海洛因或IMF,而NMURx的这一比例为1.05% (95% CI: 0.97%, 1.14%)。在回归模型中,兴奋剂和苯二氮卓类药物的使用始终与两次调查中海洛因或IMF使用的增加有关。结论和相关性:与NSDUH相比,NMURx中海洛因或IMF使用的估计流行率高出近50%。这些结果强调了使用补充性监测方法以准确估计海洛因或国际货币基金组织使用的流行程度和模式的重要性。
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来源期刊
Addiction Science & Clinical Practice
Addiction Science & Clinical Practice Psychology-Clinical Psychology
CiteScore
3.90
自引率
10.80%
发文量
64
审稿时长
28 weeks
期刊介绍: Addiction Science & Clinical Practice provides a forum for clinically relevant research and perspectives that contribute to improving the quality of care for people with unhealthy alcohol, tobacco, or other drug use and addictive behaviours across a spectrum of clinical settings. Addiction Science & Clinical Practice accepts articles of clinical relevance related to the prevention and treatment of unhealthy alcohol, tobacco, and other drug use across the spectrum of clinical settings. Topics of interest address issues related to the following: the spectrum of unhealthy use of alcohol, tobacco, and other drugs among the range of affected persons (e.g., not limited by age, race/ethnicity, gender, or sexual orientation); the array of clinical prevention and treatment practices (from health messages, to identification and early intervention, to more extensive interventions including counseling and pharmacotherapy and other management strategies); and identification and management of medical, psychiatric, social, and other health consequences of substance use. Addiction Science & Clinical Practice is particularly interested in articles that address how to improve the quality of care for people with unhealthy substance use and related conditions as described in the (US) Institute of Medicine report, Improving the Quality of Healthcare for Mental Health and Substance Use Conditions (Washington, DC: National Academies Press, 2006). Such articles address the quality of care and of health services. Although the journal also welcomes submissions that address these conditions in addiction speciality-treatment settings, the journal is particularly interested in including articles that address unhealthy use outside these settings, including experience with novel models of care and outcomes, and outcomes of research-practice collaborations. Although Addiction Science & Clinical Practice is generally not an outlet for basic science research, we will accept basic science research manuscripts that have clearly described potential clinical relevance and are accessible to audiences outside a narrow laboratory research field.
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