Validation of Recalibrated TONOVET Plus and TONOVET Pro in Canine Eyes Compared to Manometer and TONOVET.

IF 1.7 4区农林科学 Q2 VETERINARY SCIENCES

Veterinary ophthalmology Pub Date : 2025-02-11 DOI:10.1111/vop.70002

Jiwon Lee, Wontae Kim, Jaeho Shim, Yujin Kim, Seonmi Kang, Young-Kyoung Yoo, Young-Ho Lee, Kangmoon Seo

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引用次数: 0

Abstract

Objective: To evaluate the accuracy of recalibrated TONOVET Plus (rTVP) and the newly released TONOVET Pro (TVPR) in measuring intraocular pressure (IOP) in ex vivo canine eyes compared to manometer and the established TONOVET (TV).

Procedure: Sixteen enucleated canine eyes were cannulated to establish manometric IOPs ranging from 5 to 80 mmHg. IOP measurements were obtained using TV, rTVP, and TVPR.

Results: All tonometers showed a strong correlation with the manometer (R² > 0.98). Measurements from rTVP and TVPR exhibited almost perfect agreement with the manometer (CCC = 0.9974 for both), whereas TV demonstrated lower agreement (CCC = 0.9874) associated with greater systematic bias. Specifically, TV showed a lower proportional bias (95% confidence interval [CI] of the slope = 0.987-1.006) but a larger systematic bias (intercept = -3.33 mmHg) compared to rTVP and TVPR (95% CI of the slope = 1.045-1.066 and 1.045-1.063; intercept = -2.532 and -2.633 mmHg, respectively). In accuracy analyses by range, rTVP and TVPR showed no significant difference from the manometer in the 30-70 mmHg and 35-80 mmHg IOP ranges, respectively.

Conclusions: Among the ICare rebound tonometers, rTVP and TVPR provided the most accurate IOP measurements in the ex vivo analysis and demonstrated particularly strong agreement in the high IOP range, suggesting their suitability for IOP measurement in glaucomatous patients.

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重新校准的TONOVET Plus和TONOVET Pro在犬眼上与压力计和TONOVET的比较验证。

目的：评价重新校准的TONOVET Plus （rTVP）和新发布的TONOVET Pro （TVPR）测量离体犬眼内眼压（IOP）的准确性，并与眼压计和现有的TONOVET （TV）进行比较。步骤：对16只去核犬眼进行插管，测定眼压IOPs，范围从5到80 mmHg。IOP测量采用TV、rTVP和TVPR。结果：血压计与血压计有较强的相关性（R2 > 0.98）。rTVP和TVPR的测量结果与压力计几乎完全一致（两者的CCC = 0.9974），而TV显示出较低的一致性（CCC = 0.9874），与较大的系统偏差相关。具体而言，与rTVP和TVPR相比，TV表现出较低的比例偏差（95%置信区间[CI]斜率= 0.987-1.006），但系统偏差（截距= -3.33 mmHg）较大(95% CI斜率= 1.045-1.066和1.045-1.063；intercept = -2.532和-2.633 mmHg)。在范围精度分析中，rTVP和TVPR分别在30-70 mmHg和35-80 mmHg IOP范围内与压力计无显著差异。结论：在ICare反跳眼压计中，rTVP和TVPR在离体分析中提供了最准确的IOP测量，并在高IOP范围内表现出特别强的一致性，表明它们适用于青光眼患者的IOP测量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary ophthalmology 农林科学-兽医学

CiteScore

2.70

自引率

37.50%

发文量

审稿时长

12-24 weeks

期刊介绍： Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.