Detection of protozoa in drinking water using SPR biosensor employing titanium dioxide and MXene nanomaterial

IF 2.2 4区工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC

Journal of Computational Electronics Pub Date : 2025-02-13 DOI:10.1007/s10825-025-02280-y

Malek G. Daher, Sofyan A. Taya, Osama S. Faragallah, Shobhit K. Patel, Yogenra Kumar Prajapati, Ammar Armghan

{"title":"Detection of protozoa in drinking water using SPR biosensor employing titanium dioxide and MXene nanomaterial","authors":"Malek G. Daher, Sofyan A. Taya, Osama S. Faragallah, Shobhit K. Patel, Yogenra Kumar Prajapati, Ammar Armghan","doi":"10.1007/s10825-025-02280-y","DOIUrl":null,"url":null,"abstract":"<div><p>Water is one of the essential requirements for human life. Various types of impurities that are present in the drinking water can produce grave health concerns, affect body tissues, and may lead to death. Protozoan parasites are one of the major biological pollutants in the water, which are ordinarily transferred across during the oral-fecal path. <i>Cryptosporidium parvum</i> oocysts (CPO) and <i>Giardia lamblia</i> (GL) are two frequently observed waterborne protozoan organisms. They have different values of index of refraction (IOR). Novel detector can be established with real-time detection based on this biophysical consideration. Here, an optical surface plasmon resonance biosensor (OSPRB) is developed for discovery of CPO and GL in drinking water. Angular examination and Kretschmann design are employed to explain the conception of the setup. An angular sensitivity (AS) of 188 Deg./RIU is attained by the suggested OSPRB with very low limit of detection (LOD) of 2.64 × 10<sup>−5</sup> RIU. Other functioning factors are calculated for offered OSPRB. The achieved outcomes indicate that the suggested OSPRB has conspicuously improved performance as contrasted to aforementioned outcomes in the literatures. The suggested OSPRB can accelerate a substantial biological detecting tool with accurate and fast sensing at early point.</p></div>","PeriodicalId":620,"journal":{"name":"Journal of Computational Electronics","volume":"24 2","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Computational Electronics","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s10825-025-02280-y","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}

引用次数: 0

Abstract

Water is one of the essential requirements for human life. Various types of impurities that are present in the drinking water can produce grave health concerns, affect body tissues, and may lead to death. Protozoan parasites are one of the major biological pollutants in the water, which are ordinarily transferred across during the oral-fecal path. Cryptosporidium parvum oocysts (CPO) and Giardia lamblia (GL) are two frequently observed waterborne protozoan organisms. They have different values of index of refraction (IOR). Novel detector can be established with real-time detection based on this biophysical consideration. Here, an optical surface plasmon resonance biosensor (OSPRB) is developed for discovery of CPO and GL in drinking water. Angular examination and Kretschmann design are employed to explain the conception of the setup. An angular sensitivity (AS) of 188 Deg./RIU is attained by the suggested OSPRB with very low limit of detection (LOD) of 2.64 × 10⁻⁵ RIU. Other functioning factors are calculated for offered OSPRB. The achieved outcomes indicate that the suggested OSPRB has conspicuously improved performance as contrasted to aforementioned outcomes in the literatures. The suggested OSPRB can accelerate a substantial biological detecting tool with accurate and fast sensing at early point.

查看原文本刊更多论文

利用二氧化钛和 MXene 纳米材料的 SPR 生物传感器检测饮用水中的原生动物

水是人类生活的基本需求之一。饮用水中存在的各种杂质会产生严重的健康问题，影响身体组织，并可能导致死亡。原生动物寄生虫是水中主要的生物污染物之一，通常通过口腔-粪便途径传播。小隐孢子虫卵囊（CPO）和贾第鞭毛虫（GL）是两种常见的水生原生动物。它们的折射率（IOR）值不同。基于这种生物物理的考虑，可以建立实时检测的新型检测器。本文研制了一种用于饮用水中CPO和GL检测的光学表面等离子体共振生物传感器（OSPRB）。采用角度检验和克雷茨曼设计来解释装置的概念。该方法的角灵敏度（AS）为188°/RIU，检测限（LOD）为2.64 × 10−5 RIU。为提供的OSPRB计算其他功能因子。结果表明，与上述文献结果相比，建议的OSPRB具有显著的性能提高。所提出的OSPRB可以加速一个重要的生物检测工具，具有准确和快速的早期传感。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Computational Electronics ENGINEERING, ELECTRICAL & ELECTRONIC-PHYSICS, APPLIED

CiteScore

4.50

自引率

4.80%

发文量

142

审稿时长

>12 weeks

期刊介绍： he Journal of Computational Electronics brings together research on all aspects of modeling and simulation of modern electronics. This includes optical, electronic, mechanical, and quantum mechanical aspects, as well as research on the underlying mathematical algorithms and computational details. The related areas of energy conversion/storage and of molecular and biological systems, in which the thrust is on the charge transport, electronic, mechanical, and optical properties, are also covered. In particular, we encourage manuscripts dealing with device simulation; with optical and optoelectronic systems and photonics; with energy storage (e.g. batteries, fuel cells) and harvesting (e.g. photovoltaic), with simulation of circuits, VLSI layout, logic and architecture (based on, for example, CMOS devices, quantum-cellular automata, QBITs, or single-electron transistors); with electromagnetic simulations (such as microwave electronics and components); or with molecular and biological systems. However, in all these cases, the submitted manuscripts should explicitly address the electronic properties of the relevant systems, materials, or devices and/or present novel contributions to the physical models, computational strategies, or numerical algorithms.