Study of N-Acetylamino Saccharides with Synchrotron-Based Ultraviolet Resonance Raman Spectroscopy: In Combination with ATR Far-Ultraviolet Spectroscopy

IF 4.8 2区化学 Q2 CHEMISTRY, PHYSICAL

The Journal of Physical Chemistry Letters Pub Date : 2025-02-12 DOI:10.1021/acs.jpclett.4c03435

Kosuke Hashimoto, Fatima Matroodi, Soh Morimatsu, Barbara Rossi, Yusuke Morisawa, Yukihiro Ozaki, Hidetoshi Sato

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Abstract

We investigate resonance (true resonance and pre-resonance) Raman (RR) effects in glucose, galactose, N-acetylglucosamine, and N-acetylgalactosamine with ultraviolet resonance Raman (UVRR) and far-ultraviolet (FUV) spectroscopies. Electronic transitions in the FUV region are attributed to electronic orbitals due to σ and π electrons. Their geometric orientations that participate in the resonance effect have not yet been well studied, unlike those for visible and near-infrared RR spectroscopies. In this study, we have employed monosaccharides and their derivatives with an amino group, which has strong FUV absorption near 190 nm. Quantum chemical calculation indicates that the band at 190 nm consists of multiple electric transitions. Their UVRR spectra measured with 213, 226, and 250 nm excitation suggest that Raman bands due to the amino group are enhanced via multiple electronic transitions, but those due to the saccharide groups are enhanced slightly. The results demonstrate that a combined study with UVRR and FUV spectroscopies provides new insights into the geometry and symmetry of the electronic transitions in σ and π orbitals.

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来源期刊

The Journal of Physical Chemistry Letters CHEMISTRY, PHYSICAL-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

9.60

自引率

7.00%

发文量

1519

审稿时长

1.6 months

期刊介绍： The Journal of Physical Chemistry (JPC) Letters is devoted to reporting new and original experimental and theoretical basic research of interest to physical chemists, biophysical chemists, chemical physicists, physicists, material scientists, and engineers. An important criterion for acceptance is that the paper reports a significant scientific advance and/or physical insight such that rapid publication is essential. Two issues of JPC Letters are published each month.