Highly Stretchable 3D Microelectrode Array for Noninvasive Functional Evaluation of Cardiac Spheroids and Midbrain Organoids (Adv. Mater. 6/2025)

Abstract

Stretchable Microelectrode Array

In article number 2412953, Kiup Kim and co-workers introduce a highly stretchable 3D MEA with PEDOT:PSS protruding microelectrodes structurally designed to ensure a reliable and stable interface with organoids even under buoyant forces in media. This design achieves high SNR electrophysiological signals, enabling precise and non-invasive functional assessments of organoids. The system demonstrates significant potential for drug screening and disease modeling.