All-Optical Microfluidic Technology Enabled by Photodeformable Linear Liquid Crystal Polymers

Abstract

The microfluidic biochemical/immunoassay systems typically consist of microfluidic chips, fluid driving devices, and detection components. The core of the system is the microfluidic chips based on microfluidic technology, which are typically constructed with nonresponsive materials such as silicon, glass, and rigid plastics, thus requiring complex external air/liquid pumps to manipulate the samples. The external equipment renders the microfluidic systems cumbersome and increases the risk of biosample contamination. The all-optical microfluidic chip (AOMC) integrates all necessary microfluidic units and uses light to manipulate microfluids, which has the potential to completely solve the major problems of miniaturization and integration in microfluidic systems. The photocontrolled manipulation in AOMCs facilitates contactless interaction with liquids, eliminating the need for physical interconnects such as complex external electric, hydraulic, or pneumatic devices and replacing the traditional microfluidic components such as pumps, mixers, and separators, which offers AOMCs improved flexibility, robustness, and portability. However, impeded by photocontrolled principles and appropriate materials, AOMCs and photocontrolled biochemical/immunoassay analyzers have never been created.