{"title":"[Arterial hypertension is an oxidative stress, as a pathogenetic target for the treatment of chronic cerebrovascular insufficiency].","authors":"E I Chukanova, A S Chukanova, D D Andrianov","doi":"10.17116/jnevro202512501184","DOIUrl":null,"url":null,"abstract":"<p><p>The increase in the development of arterial hypertension (AH), as the main modifiable risk factor for the development of acute and chronic cerebral circulatory insufficiency, often leading to a progressive decrease in cognitive status and physical activity, requires early detection and effective pathogenetic therapy. The breadth of therapeutic effects of the drug Mexidol (ethylmethylhydroxypyridine succinate) due to the multifactorial nature of its pathogenetic effects contributes to its widespread use. The safe profile of Mexidol use and the absence of drug interaction makes it relevant in the complex treatment of patients with cardiovascular diseases.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"125 1","pages":"84-90"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17116/jnevro202512501184","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The increase in the development of arterial hypertension (AH), as the main modifiable risk factor for the development of acute and chronic cerebral circulatory insufficiency, often leading to a progressive decrease in cognitive status and physical activity, requires early detection and effective pathogenetic therapy. The breadth of therapeutic effects of the drug Mexidol (ethylmethylhydroxypyridine succinate) due to the multifactorial nature of its pathogenetic effects contributes to its widespread use. The safe profile of Mexidol use and the absence of drug interaction makes it relevant in the complex treatment of patients with cardiovascular diseases.
期刊介绍:
Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова.
Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.