Silicone Oil Tamponade in the Management of Endogenous Endophthalmitis.

IF 1.9 4区医学 Q2 OPHTHALMOLOGY

Seminars in Ophthalmology Pub Date : 2025-02-11 DOI:10.1080/08820538.2025.2459312

Constance Weber, Zoe Kiy, Katharina Wall, Frank G Holz, Raffael Liegl

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引用次数: 0

Abstract

Purpose: This study aimed to evaluate pars plana vitrectomy (ppv) with silicone oil tamponade in the management of patients with endogenous endophthalmitis.

Methods: All patients treated with ppv and silicone oil for endogenous endophthalmitis at the University Eye Hospital Bonn between 2015 and 2022 were included. We documented all preoperative data, encompassing BCVA at diagnosis, clinical observations, and presenting symptoms. During each follow-up visit, we evaluated BCVA and monitored for any complications. Statistical analysis was performed using SPSS Statistics.

Results: In total, 19 eyes of 19 patients were included in this study. The most common underlying diseases were urosepsis in 5 patients (26.3%), endocarditis and leukemia in 3 patients (15.8%) respectively. The most common bacterial pathogens in the vitreous samples were gram-positive cocci in 3 patients (15.8%) and staphylococcus aureus in 3 patients (15.8%). The most common fungal pathogen was candida albicans in two patients (10.8%). Visual acuity (VA) at diagnosis was 1.93 logMAR (0.4-3.0 logMAR) and increased to 1.39 logMAR (0.2-3.0 logMAR) after six months and 1.21 logMAR (0.2-3.0 logMAR) after one year. 2 patients (10.5%) died during the follow-up because of their underlying disease. 9 eyes (47.4%) developed postoperative complications. One eye with no light perception was enucleated due to pain caused by high intraocular pressure. 2 eyes (10.5%) developed a postoperative retinal detachment needing further surgery.

Conclusion: Most patients treated with ppv and silicone oil for endogenous endophthalmitis experienced an improvement in visual acuity; however, due to the severity of the condition, the visual prognosis remains guarded.

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硅油填塞治疗内源性眼内炎。

目的：探讨硅油填塞玻璃体切割术治疗内源性眼内炎的疗效。方法：纳入2015年至2022年在波恩大学眼科医院接受ppv和硅油治疗内源性眼内炎的所有患者。我们记录了所有术前数据，包括诊断时的BCVA、临床观察和表现症状。在每次随访中，我们评估BCVA并监测任何并发症。采用SPSS统计软件进行统计学分析。结果：本研究共纳入19例患者19只眼。最常见的基础疾病为尿脓毒症5例（26.3%），心内膜炎和白血病3例（15.8%）。玻璃体标本中最常见的病原菌为革兰氏阳性球菌3例（15.8%）和金黄色葡萄球菌3例（15.8%）。2例患者最常见的真菌病原体为白色念珠菌（10.8%）。诊断时的视力（VA）为1.93 logMAR (0.4-3.0 logMAR)， 6个月后增加到1.39 logMAR (0.2-3.0 logMAR)， 1年后增加到1.21 logMAR （0.2-3.0 logMAR）。2例（10.5%）患者在随访期间因其基础疾病死亡。术后并发症9眼（47.4%）。由于高眼压引起的疼痛，一只无光感的眼睛去核。2只眼（10.5%）发生术后视网膜脱离，需要进一步手术。结论：应用ppv联合硅油治疗内源性眼内炎患者视力均有明显改善；然而，由于病情的严重性，视力预后仍然是谨慎的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Seminars in Ophthalmology offers current, clinically oriented reviews on the diagnosis and treatment of ophthalmic disorders. Each issue focuses on a single topic, with a primary emphasis on appropriate surgical techniques.