The Effectiveness of Functional Septorhinoplasty in Improving COVID-19-related Olfactory Dysfunction.

IF 1.1 4区医学 Q3 SURGERY

Facial Plastic Surgery Pub Date : 2025-02-24 DOI:10.1055/a-2535-0153

Alfonso Luca Pendolino, Bruno Scarpa, Peter J Andrews

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引用次数: 0

Abstract

Long-Term COVID-19-related olfactory dysfunction (C19OD) remains a significant challenge with no established treatment providing meaningful improvement. This study aimed to assess the efficacy of functional septorhinoplasty (fSRP) in improving olfactory dysfunction in patients with persistent C19OD compared to a control group undergoing olfactory training (OT). In this prospective study patients with persistent C19OD undergoing fSRP were enrolled while those declining surgery continued with OT as the control group. Patients were followed for six months with olfactory function assessed using Sniffin' Sticks (S'S) and nasal airflow evaluated through peak nasal inspiratory flow (PNIF) and acoustic rhinometry (AR). Among the participants 12 underwent fSRP while 13 were in the control group. Significant improvements (p < 0.05) in all S'S scores were observed in the fSRP group but not in the control group. TDI scores improved above the minimal clinically important difference only in the fSRP group. Strong correlations were found between olfactory scores and nasal measurements. Comparison of olfactory threshold gains between groups revealed a statistically significant benefit in the fSRP group. These findings suggest that fSRP can significantly improve persistent C19OD providing a notable olfactory threshold gain compared to OT.

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功能性鼻中隔成形术改善covid -19相关嗅觉功能障碍的疗效

目前尚未满足的需求是找到一种治疗方法，可以为长期（bb10 - 2年）covid -19相关嗅觉功能障碍（C19OD）患者实现有意义的嗅觉改善。目的与假设：评价fSRP改善持续性C19OD患者OD的疗效。数据与对照组C19OD患者嗅觉训练（OT）进行比较。研究设计：前瞻性对照队列研究方法：纳入接受fSRP治疗的持续性C19OD患者。拒绝fSRP的患者继续OT（对照组）。随访6个月。用嗅探棒（S'S）测量嗅觉。采用峰值鼻吸气流量（PNIF）和声学鼻测量（AR）对鼻气道进行评估。结果：12例患者行fSRP治疗，13例为对照组。结论：我们的初步研究表明，与OT相比，fSRP可以显著改善持续性C19OD，并增加显著的嗅觉阈值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Facial Plastic Surgery 医学-外科

CiteScore

1.80

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Facial Plastic Surgery is a journal that publishes topic-specific issues covering areas of aesthetic and reconstructive plastic surgery as it relates to the head, neck, and face. The journal''s scope includes issues devoted to scar revision, periorbital and mid-face rejuvenation, facial trauma, facial implants, rhinoplasty, neck reconstruction, cleft palate, face lifts, as well as various other emerging minimally invasive procedures. Authors provide a global perspective on each topic, critically evaluate recent works in the field, and apply it to clinical practice.