A Review of the Progress in the Diagnosis and Treatment of Pulmonary Sarcomatoid Carcinoma.

IF 2.3 4区 医学 Q3 ONCOLOGY
Dongying Liao, Jiayu Liu, Qingpeng Jin, Xiaoqun Wang, Na Wang, Yingjie Jia, Fanming Kong
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引用次数: 0

Abstract

Pulmonary sarcomatoid carcinoma(PSC)is a rare pathological type of non-small cell lung cancer that combines the characteristics of epithelial and mesenchymal tu-mors and is an extremely malignant and highly heterogeneous malignant tumor. PSC is dif-ficult to diagnose and has a poor sensitivity to radiotherapy. In recent years, with the effica-cy breakthroughs of molecularly targeted drugs and immune checkpoint inhibitors in tumor therapy, the treatment of PSC is gradually exploring precise targeted therapy and immuno-therapy. In this article, we will provide a comprehensive review of the clinical features, di-agnostic points, and progress in the clinical therapeutic research of PSC. We hope to provide guidance and help with clinical treatment and scientific research.

肺肉瘤样癌的诊断与治疗进展综述。
肺肉瘤样癌(Pulmonary sarcomatoid carcinoma, PSC)是一种罕见的非小细胞肺癌病理类型,兼具上皮性和间充质肿瘤的特点,是一种极恶性、高度异质性的恶性肿瘤。PSC诊断困难,对放疗敏感性差。近年来,随着分子靶向药物和免疫检查点抑制剂在肿瘤治疗中的疗效突破,PSC的治疗正在逐步探索精准靶向治疗和免疫治疗。本文就PSC的临床特点、诊断要点及临床治疗研究进展作一综述。我们希望为临床治疗和科研提供指导和帮助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current cancer drug targets
Current cancer drug targets 医学-肿瘤学
CiteScore
5.40
自引率
0.00%
发文量
105
审稿时长
1 months
期刊介绍: Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes. Current Cancer Drug Targets publishes original research articles, letters, reviews / mini-reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cancer. As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.
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