Synthesis of carbon quantum dots from “De-oiled copra cake” by hydrothermal mechanism: In the realm of bioimaging

Brindha Matharasi Murugan , Suneesha Vazhangodan Abdul Saleem , Gopi Palani Selvan , T. Siva Vijayakumar , Sowmiya Prakash , Gnanadesigan Murugesan
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Abstract

This study incorporates an efficient facile one-pot hydrothermal synthesis of carbon quantum dots (CQD-CK) using the de-oiled copra cake biowaste. The synthesized quantum dots have showed good bioimaging with distinguished fluorescence cell properties with bacterial cultures (Escherichia coli and Streptococcus pyogenes), and yeast cells (Saccharomyces cerevisiae). Throughout the zebrafish's embryonic stages, the synthesized CQD-CK displayed unique fluorescence, indicating the CQD-CKs' increased binding affinities towards the zebrafish's tissues. The optical (UV, PL and FT-IR) and morphological studies (Zeta Potential (ZP), HR-TEM, SEM-EDAX, XRD, Raman spectroscopy) of the synthesized CQD-CK, further confirms the quantum nature of the synthesized CQD-CK (0.262nm through FFT). This work shows that the optical and morphological properties of the synthesized CQD-CK, as well as their synchronized outcomes in the bacterial and live zebrafish embryo and larval imaging, may make them a valuable probe in drug screening, medical research, and toxicological studies.
水热机制合成“去油椰子饼”碳量子点:在生物成像领域
本研究采用一锅水热法快速高效地合成了碳量子点(CQD-CK)。合成的量子点在细菌培养物(大肠杆菌和化脓性链球菌)和酵母细胞(酿酒酵母)中显示出良好的荧光细胞特性。在整个斑马鱼的胚胎阶段,合成的CQD-CK显示出独特的荧光,表明CQD-CK对斑马鱼组织的结合亲和力增加。对合成的CQD-CK进行了光学(UV、PL、FT-IR)和形态学(Zeta Potential (ZP)、HR-TEM、SEM-EDAX、XRD、拉曼光谱)研究,进一步证实了合成的CQD-CK的量子性(通过FFT表征0.262nm)。这项工作表明,合成的CQD-CK的光学和形态学特性,以及它们在细菌和活斑马鱼胚胎和幼虫成像中的同步结果,可能使它们在药物筛选、医学研究和毒理学研究中成为有价值的探针。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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