Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.

npj women's health Pub Date : 2025-01-01 Epub Date: 2025-02-06 DOI:10.1038/s44294-024-00052-w
Camran R Nezhat, Tomiko T Oskotsky, Joshua F Robinson, Susan J Fisher, Angie Tsuei, Binya Liu, Juan C Irwin, Brice Gaudilliere, Marina Sirota, David K Stevenson, Linda C Giudice
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Abstract

Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.

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