Comparison of reoperation incidence after fusion versus decompression for lumbar degenerative disease: A propensity score-weighted study.

Annals of clinical epidemiology Pub Date : 2024-10-31 eCollection Date: 2025-01-01 DOI:10.37737/ace.25001
Soichiro Masuda, Toshiki Fukasawa, Shunsuke Fujibayashi, Bungo Otsuki, Koichi Murata, Takayoshi Shimizu, Shuichi Matsuda, Koji Kawakami
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Abstract

Background: Reoperation after lumbar spine surgery is a major issue for both patients and physicians. It is uncertain whether fusion is superior to decompression alone for lumbar degenerative disease regarding reoperation rate. We aim to evaluate the reoperation rate after fusion surgery for lumbar degenerative disease compared with decompression alone.

Methods: This study was conducted under a retrospective cohort design in patients undergoing fusion or decompression alone in one or two levels for lumbar degenerative disease using a Japanese claims-based database. Primary outcome was reoperation incidence during the follow-up period, and secondary outcome was reoperation incidence within 90 days postoperatively. Confounding factors were handled using propensity score overlap weighting. Cumulative incidence of reoperation was calculated from the Kaplan-Meier curve and hazard ratios (HRs) and 95% confidence intervals (CIs) for reoperation were estimated using Cox proportional hazards regression models.

Results: 8497 patients (2051 patients in the fusion group and 6446 in the decompression alone group) were included in the study. There was no difference in reoperation rate between fusion and decompression alone (weighted HR 0.85 [95% CI 0.69 to 1.04]; p = 0.11).

Conclusions: Among patients with lumbar degenerative disease who underwent fusion or decompression alone, no significant difference was observed between the two groups.

腰椎退行性疾病融合与减压后再手术发生率的比较:一项倾向评分加权研究。
背景:腰椎手术后再手术是困扰患者和医生的主要问题。对于腰椎退行性疾病的再手术率,融合是否优于单纯减压尚不确定。我们的目的是评估腰椎退行性疾病融合手术后的再手术率与单纯减压手术的比较。方法:本研究采用回顾性队列设计,使用基于日本索赔的数据库,在腰椎退行性疾病的患者中进行一段或两段单独融合或减压。主要观察指标为随访期间的再手术发生率,次要观察指标为术后90天内的再手术发生率。使用倾向得分重叠加权处理混杂因素。根据Kaplan-Meier曲线计算再手术的累积发生率,使用Cox比例风险回归模型估计再手术的风险比(hr)和95%置信区间(ci)。结果:共纳入8497例患者,其中融合组2051例,单纯减压组6446例。单纯融合术与减压术的再手术率无差异(加权HR 0.85 [95% CI 0.69 ~ 1.04];P = 0.11)。结论:腰椎退行性疾病患者单独行融合术或减压术,两组间无显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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