Ahtesham A Qurishi, Mohammed S Al Dira, Amal H Sholan, Shahad E Abzoah, Mahdi A Hakami, Emad Malhan, Shahad M Moafa
{"title":"Effect of Different Pediatric Medications on RMGIC: A Comparative Study.","authors":"Ahtesham A Qurishi, Mohammed S Al Dira, Amal H Sholan, Shahad E Abzoah, Mahdi A Hakami, Emad Malhan, Shahad M Moafa","doi":"10.4103/jpbs.jpbs_688_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material's durability and effectiveness.</p><p><strong>Methodology: </strong>Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey's test.</p><p><strong>Results: </strong>All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes.</p><p><strong>Conclusion: </strong>Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3185-S3187"},"PeriodicalIF":0.7000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805132/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of pharmacy & bioallied sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jpbs.jpbs_688_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/11 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material's durability and effectiveness.
Methodology: Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey's test.
Results: All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes.
Conclusion: Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
