Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-12-10 DOI:10.4103/jpbs.jpbs_1270_24
Ritesh Upadhyay, Annasaheb J Dhumale, Chanchlesh Dehariya, Renu Waghmare, Amit Rangari
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Abstract

Background: The National Malaria Elimination Program (NMEP) has helped reduce the mortality from malaria in India, and there are alarmingly high mortality rates from anemia in certain geographical regions.

Aim: To assess the clinical, laboratory, and sociodemographic factors associated with malaria from P. falciparum and P. vivax.

Methods: This retrospective record-based clinical study subjects with malaria were further divided into P. vivax and P. falciparum cases. In all the cases, the clinical, laboratory, and sociodemographic factors were assessed. Data gathered were analyzed statistically.

Results: During the study period, 222 cases of malaria were assessed where 22.52% (n = 50) and 74.48% (n = 172) cases were due to P. falciparum and P. vivax, respectively. Hepatomegaly was common in P. falciparum cases and splenomegaly in P. vivax cases. Thrombocytopenia was seen in 58.1% (n = 100) and 72% (n = 36) subjects with P. vivax and P. falciparum cases. No significant difference was seen in other laboratory parameters.

Conclusions: Clinical, laboratory, and sociodemographic factors associated with malaria from P. falciparum and P. vivax have no statistically significant difference.

探讨与疟疾相关的临床、实验室和社会人口因素:一项病例对照研究。
背景:国家疟疾消除规划(NMEP)帮助降低了印度疟疾死亡率,在某些地理区域,贫血死亡率高得惊人。目的:评估恶性疟原虫和间日疟原虫引起的疟疾的临床、实验室和社会人口学因素。方法:以回顾性记录为基础,将临床研究对象进一步分为间日疟原虫和恶性疟原虫。对所有病例的临床、实验室和社会人口因素进行了评估。对收集的数据进行统计分析。结果:研究期间共检测疟疾222例,其中恶性疟和间日疟分别占22.52% (n = 50)和74.48% (n = 172)。肝肿大常见于恶性疟原虫,脾肿大常见于间日疟原虫。间日疟原虫和恶性疟原虫患者中血小板减少率分别为58.1% (n = 100)和72% (n = 36)。其他实验室参数无显著差异。结论:与恶性疟原虫和间日疟原虫疟疾相关的临床、实验室和社会人口学因素无统计学差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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