Enhanced Hair Regrowth Through Dual-Wavelength Low-Level Laser Therapy: A Comparative Study on Mice

Abstract

Low-level laser therapy (LLLT) is a non-invasive treatment that uses low-power lasers or light sources to stimulate biological responses. Previous studies focused on single-wavelength effects on hair growth in mice. In this study, we investigated dual-wavelength combinations to enhance hair regrowth. Using light-emitting diodes (LEDs) at 670, 680, 780, and 880 nm, we assessed the correlation between different wavelength pairs and hair regrowth after shaving in mice. Phototherapy was conducted over 14 days, with results analyzed through surface image analysis and histological examination. Our findings indicate that dual-wavelength therapy is superior to single-wavelength treatment and significantly more effective than the untreated control, demonstrating its potential for improved hair regrowth.