A pilot study of twice-weekly group-based written exposure therapy for veterans in residential substance use treatment: effects on PTSD and depressive symptoms.

IF 3.2 2区 医学 Q1 SUBSTANCE ABUSE
Natalia Van Doren, Fang-Hsi Chang, Amanda Nguyen, Kevin R McKenna, Derek D Satre, Shannon Wiltsey-Stirman
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Abstract

Background: Posttraumatic stress disorder (PTSD) is highly comorbid with substance use disorders (SUDs), resulting in high prevalence of PTSD among individuals in residential SUD care. However, there is limited research on integrating trauma treatment into residential SUD care settings. The aim of the present project was to conduct an initial evaluation of the effects of group-based Written Exposure Therapy (WET) on PTSD and depressive symptoms that was integrated into programming for individuals in residential SUD treatment.

Methods: Participants were 48 Veterans with comorbid PTSD-SUD from a 28 day residential SUD program at a Veterans Affairs Medical Center. Eligible participants were enrolled in 5 sessions of WET, delivered twice-weekly in an adapted group format. PTSD symptoms and depressive symptoms were assessed at each session with the Posttraumatic Stress Disorder Checklist, DSM-5 version (PCL-5) and the Patient Health Questionnaire (PHQ-9).

Results: Over 5 months, 76.2% of the target population were successfully enrolled. Of the enrolled sample, 48 participants, 92% (n = 44) completed 3 sessions, while 56% (n = 28) completed 5 sessions. Generalized Estimating Equations (GEE) showed significant within-person reductions in PTSD symptoms over time, with an average decrease of 3.18 per session (χ² = 23.21, p = .006) and moderate effect sizes (d = 0.46 and d = 0.51 at mid- and post-treatment). In addition, there were significant reductions in depressive symptoms within-persons over time, with an average per-session reduction of 1.13 (χ² = 23.10, p = .006).

Conclusion: Findings demonstrate that brief, group-delivered WET is feasible and shows promise for addressing PTSD and depressive symptoms in residential SUD treatment. Results of the present evaluation could inform further efficacy testing and implementation of PTSD treatment into residential SUD settings.

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退伍军人住院药物使用治疗中每周两次以小组为基础的书面暴露疗法的初步研究:对PTSD和抑郁症状的影响。
背景:创伤后应激障碍(PTSD)与物质使用障碍(SUD)高度共病,导致住院SUD护理个体中PTSD的高患病率。然而,将创伤治疗纳入住院SUD护理环境的研究有限。本项目的目的是对基于小组的书面暴露疗法(WET)对创伤后应激障碍和抑郁症状的影响进行初步评估,并将其纳入住院治疗个体的程序设计中。方法:参与者为48名合并PTSD-SUD的退伍军人,来自退伍军人事务医疗中心为期28天的住院SUD项目。符合条件的参与者参加了5次WET,每周两次以适应的小组形式进行。采用创伤后应激障碍检查表、DSM-5版(PCL-5)和患者健康问卷(PHQ-9)对创伤后应激障碍症状和抑郁症状进行评估。结果:在5个月的时间里,76.2%的目标人群成功入组。在登记的样本中,48名参与者,92% (n = 44)完成了3个疗程,56% (n = 28)完成了5个疗程。广义估计方程(GEE)显示,随着时间的推移,PTSD症状在人体内显著减少,每次治疗平均减少3.18 (χ²= 23.21,p = 0.006),效果适中(治疗中期和治疗后d = 0.46和d = 0.51)。此外,随着时间的推移,患者体内抑郁症状显著减少,平均每次治疗减少1.13例(χ 2 = 23.10, p = 0.006)。结论:研究结果表明,简短的、小组交付的WET是可行的,并且在住宅SUD治疗中显示出解决PTSD和抑郁症状的希望。本研究的结果可以为进一步的疗效测试和PTSD治疗在住宅SUD环境中的实施提供信息。
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来源期刊
Addiction Science & Clinical Practice
Addiction Science & Clinical Practice Psychology-Clinical Psychology
CiteScore
3.90
自引率
10.80%
发文量
64
审稿时长
28 weeks
期刊介绍: Addiction Science & Clinical Practice provides a forum for clinically relevant research and perspectives that contribute to improving the quality of care for people with unhealthy alcohol, tobacco, or other drug use and addictive behaviours across a spectrum of clinical settings. Addiction Science & Clinical Practice accepts articles of clinical relevance related to the prevention and treatment of unhealthy alcohol, tobacco, and other drug use across the spectrum of clinical settings. Topics of interest address issues related to the following: the spectrum of unhealthy use of alcohol, tobacco, and other drugs among the range of affected persons (e.g., not limited by age, race/ethnicity, gender, or sexual orientation); the array of clinical prevention and treatment practices (from health messages, to identification and early intervention, to more extensive interventions including counseling and pharmacotherapy and other management strategies); and identification and management of medical, psychiatric, social, and other health consequences of substance use. Addiction Science & Clinical Practice is particularly interested in articles that address how to improve the quality of care for people with unhealthy substance use and related conditions as described in the (US) Institute of Medicine report, Improving the Quality of Healthcare for Mental Health and Substance Use Conditions (Washington, DC: National Academies Press, 2006). Such articles address the quality of care and of health services. Although the journal also welcomes submissions that address these conditions in addiction speciality-treatment settings, the journal is particularly interested in including articles that address unhealthy use outside these settings, including experience with novel models of care and outcomes, and outcomes of research-practice collaborations. Although Addiction Science & Clinical Practice is generally not an outlet for basic science research, we will accept basic science research manuscripts that have clearly described potential clinical relevance and are accessible to audiences outside a narrow laboratory research field.
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