Risk Factors for the Occurrence of Depressive Disorders in Pediatric Patients With Tuberculosis.

IF 1.7 Q2 PEDIATRICS
Pediatric health, medicine and therapeutics Pub Date : 2025-02-05 eCollection Date: 2025-01-01 DOI:10.2147/PHMT.S495914
Oana Mariana Mihailov, Loredana Stavar Matei, George Tocu, Anamaria Ciubara, Raul Mihailov
{"title":"Risk Factors for the Occurrence of Depressive Disorders in Pediatric Patients With Tuberculosis.","authors":"Oana Mariana Mihailov, Loredana Stavar Matei, George Tocu, Anamaria Ciubara, Raul Mihailov","doi":"10.2147/PHMT.S495914","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is one of the oldest and most persistent infectious diseases, continuing to pose a significant public health challenge worldwide. Children diagnosed with TB are particularly vulnerable to developing depressive disorders, which can significantly reduce their quality of life and negatively affect treatment adherence and recovery. This study aimed to identify risk and prognostic factors associated with depressive disorders in pediatric patients diagnosed with tuberculosis through a prospective analysis.</p><p><strong>Materials and methods: </strong>A prospective study was conducted on 190 pediatric patients, aged 7 to 18 years, diagnosed with tuberculosis and treated at the Pneumophthisiology Hospital in Galați, Romania, between 2019 and 2021. The CDI (Children's Depression Inventory) was administered to assess depressive symptoms over the course of the study.</p><p><strong>Objective: </strong>The study aims to determine the prevalence of depressive disorders in children and adolescents by analyzing risk factors such as age, gender, place of origin, and access to medical services, as well as the effectiveness of CDI as a diagnostic tool. It also seeks to correlate clinical and demographic data with CDI scores and evaluate changes over time to identify solutions that support early diagnosis and intervention.</p><p><strong>Results: </strong>Out of the initial 190 patients, 158 completed the CDI, as some did not return for follow-up evaluations or declined to participate. Of these, 146 (92.4%) demonstrated clinically significant depressive symptoms. Key risk factors for depressive disorders included a rural background, male gender, and age between 15 and 18 years.</p><p><strong>Conclusion: </strong>Specific risk factors and vulnerabilities contribute to the development of depressive disorders in pediatric TB patients. Early identification and monitoring of these factors in a prospective framework are essential for improving the prognosis of both depression and tuberculosis, ultimately enhancing the overall outcomes for affected children.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"13-33"},"PeriodicalIF":1.7000,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807349/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric health, medicine and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/PHMT.S495914","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Tuberculosis (TB) is one of the oldest and most persistent infectious diseases, continuing to pose a significant public health challenge worldwide. Children diagnosed with TB are particularly vulnerable to developing depressive disorders, which can significantly reduce their quality of life and negatively affect treatment adherence and recovery. This study aimed to identify risk and prognostic factors associated with depressive disorders in pediatric patients diagnosed with tuberculosis through a prospective analysis.

Materials and methods: A prospective study was conducted on 190 pediatric patients, aged 7 to 18 years, diagnosed with tuberculosis and treated at the Pneumophthisiology Hospital in Galați, Romania, between 2019 and 2021. The CDI (Children's Depression Inventory) was administered to assess depressive symptoms over the course of the study.

Objective: The study aims to determine the prevalence of depressive disorders in children and adolescents by analyzing risk factors such as age, gender, place of origin, and access to medical services, as well as the effectiveness of CDI as a diagnostic tool. It also seeks to correlate clinical and demographic data with CDI scores and evaluate changes over time to identify solutions that support early diagnosis and intervention.

Results: Out of the initial 190 patients, 158 completed the CDI, as some did not return for follow-up evaluations or declined to participate. Of these, 146 (92.4%) demonstrated clinically significant depressive symptoms. Key risk factors for depressive disorders included a rural background, male gender, and age between 15 and 18 years.

Conclusion: Specific risk factors and vulnerabilities contribute to the development of depressive disorders in pediatric TB patients. Early identification and monitoring of these factors in a prospective framework are essential for improving the prognosis of both depression and tuberculosis, ultimately enhancing the overall outcomes for affected children.

儿童结核病患者抑郁障碍发生的危险因素。
背景:结核病(TB)是最古老和最持久的传染病之一,继续在世界范围内构成重大的公共卫生挑战。被诊断患有结核病的儿童特别容易患上抑郁症,这可显著降低他们的生活质量,并对治疗依从性和康复产生负面影响。本研究旨在通过前瞻性分析,确定与诊断为结核病的儿科患者抑郁症相关的风险和预后因素。材料和方法:对2019年至2021年期间在罗马尼亚Galați肺炎医院诊断为结核病并接受治疗的190名7至18岁儿科患者进行了一项前瞻性研究。CDI(儿童抑郁量表)用于评估研究过程中的抑郁症状。目的:本研究旨在通过分析年龄、性别、原籍地、医疗服务可及性等风险因素,以及CDI作为诊断工具的有效性,确定儿童和青少年抑郁症的患病率。它还寻求将临床和人口统计数据与CDI评分联系起来,并评估随时间的变化,以确定支持早期诊断和干预的解决方案。结果:在最初的190例患者中,158例完成了CDI,因为一些患者没有返回进行随访评估或拒绝参与。其中,146例(92.4%)表现出临床显著的抑郁症状。抑郁症的主要危险因素包括农村背景、男性、年龄在15至18岁之间。结论:特定的危险因素和脆弱性对儿童结核病患者抑郁症的发展有促进作用。在前瞻性框架中早期识别和监测这些因素对于改善抑郁症和结核病的预后至关重要,最终提高受影响儿童的总体结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信