Phototherapy in lymphoproliferative and inflammatory diseases associated with human T-lymphotropic virus.

IF 1.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-02-10 DOI:10.1093/trstmh/traf009

Brena Andrade de Lima Lobato, João Augusto Gomes de Souza Monteiro de Brito, José Maria de Castro Abreu Junior, Maísa Silva de Sousa, Carlos Augusto Moreira Silva, Thiago Xavier Carneiro, Rita Catarina Medeiros Sousa, Marília Brasil Xavier

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引用次数: 0

Abstract

Background: Dermatological manifestations affect 5% of patients with human T-lymphotropic virus (HTLV).

Methods: Thirteen patients with inflammatory or lymphoproliferative dermatological diseases, both HTLV-positive and HTLV-negative, were selected for treatment with ultraviolet B narrowband (UVB-NB) phototherapy. Clinical and histopathological evaluations were conducted before and after 120 d of phototherapy.

Results: All seven HTLV-positive patients evaluated were type 1. Clinical evaluation showed improvement in all 13 patients. In the histopathological examination, all patients with lymphoproliferative diseases and five with inflammatory diseases showed regression in most of the assessed parameters.

Conclusions: The present research suggests that UVB-NB phototherapy is a promising treatment for lymphoproliferative and inflammatory skin diseases in HTLV-1 patients.

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与人t淋巴细胞嗜性病毒相关的淋巴增生性和炎性疾病的光疗

背景：5%的人嗜t淋巴病毒（HTLV）患者有皮肤病表现。方法：选择htlv阳性和htlv阴性的炎症性或淋巴增生性皮肤病患者13例，采用UVB-NB光疗治疗。分别于光疗前后120 d进行临床和组织病理学评价。结果：7例htlv阳性患者均为1型。临床评估显示13例患者均有改善。在组织病理学检查中，所有淋巴增生性疾病患者和5例炎症性疾病患者的大部分评估参数均出现倒退。结论：UVB-NB光疗是治疗HTLV-1淋巴细胞增生性和炎症性皮肤病的一种有前景的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.