Recent developments in the mechanochemical mediated innovative approaches for cycloaddition reactions

Abstract

Over the last decade, the use of mechanical force in chemical systems, whether by mechanical grinding and milling or ultrasound, has resulted in a number of interesting outcomes, leading to the practical re-discovery of the area. The recent excitement around mechanochemistry is strongly tied to its application in relatively new areas of green and supramolecular chemistry, medicinal co-crystals, and metal-organic frameworks. The applications of mechanochemistry in more traditional disciplines such as organic synthesis, catalysis, and inorganic chemistry are as interesting and inventive. Mechanochemical-mediated cycloaddition reactions are economical, environmentally friendly, use nontoxic chemicals, and have been heavily emphasized in recent years. Hence, the current minireview summarizes the latest developments in cycloaddition reactions via mechanochemistry.