A hypoallergenic solid meal for gastric emptying scintigraphy based on mediterranean diet. "One diet to empty almost everyone".

Abstract

Aim: We aim to establish normal values and standardize a hypoallergenic and mediterranean diet for gastric emptying scintigraphy (GES).

Material and methods: In a prospective cohort of healthy volunteers, we performed GES of a [⁹⁹Tc]TcDTPA² labelled hypoallergenic meal (egg, potato, rice and olive oil). Anterior and posterior images were simultaneously acquired at 0, 30, 60, 110, 120, 130, 180, 230, 240 and 250 min. Cross-sectional analysis was performed between demographic data and gastric retention values. A score covariance analysis model was used to observer changes between measurements over time.

Results: 50 participants (29 women) were included. Mean values and standard deviation (5-95th) for gastric retention percentages at 60, 120, 180, 240 min were 51.40 ± 8.63 (36.5-66.1), 21.66 ± 9.40 (6.5-38.2), 7.58 ± 5.77 (1.5-19.1) and 2.94 ± 2.08 (1-7.3), respectively. Male participants had a significative faster gastric emptying compared to women in practically all the acquisitions. Male participants and smoker participants generated a significative decrease of gastric retention values in generalized linear model (male coefficient -4.818, IC95% -7.24 to -2.39, P-value < .001; and smoker coefficient of -3.484, IC95% -6.29 to -0.67, P-value < .05).

Conclusion: This study standardizes and establishes normal values for GES with the first hypoallergenic solid meal based on consensus recommendations and a mediterranean diet; suitable for most patients with allergic or sensitive-conditions to other meal components.