{"title":"Duplex Ultrasound in Evaluating Transplanted Renal Artery In-Stent Restenosis.","authors":"Fu-Shun Pan, Dao-Peng Yang, Rong-Hai Deng","doi":"10.1002/jum.16656","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the diagnosis performance of duplex ultrasound (DUS) in predicting transplanted renal artery (TRA) in-stent restenosis (ISR).</p><p><strong>Methods: </strong>In this retrospective study, 112 consecutive patients underwent stenting due to TRA stenosis. DUS were performed within 1 week after stenting for baseline value, and after ≥3 months follow-up for surveillance of ISR. The DUS measurements included peak systolic velocity (PSV) and PSV ratio of renal artery stent to iliac artery (RIR). Receiver operating characteristic (ROC) curves were applied to evaluate the diagnosis performance of DUS parameters in predicting ISR.</p><p><strong>Results: </strong>There were 69 patients (28 men; age, 38.3 ± 15.1 years) who obtained 92 adequate paired DUS and CTA after stenting, which were classified as ISR group (26 TRAs) and non-ISR group (66 TRAs). There was no difference between the two groups for baseline DUS features, including PSV<sub>B</sub> and RIR<sub>B</sub>. The late DUS features including stent PSV<sub>L</sub> (475.5 vs 261.9 cm/s), RIR<sub>L</sub> (4.10 vs 2.18), and stent PSV<sub>L</sub>/PSV<sub>B</sub> (2.72 vs 1.14) were significantly higher in the ISR group than the non-ISR group (all P < .0001). Stent PSV<sub>L</sub>, RIR<sub>L</sub>, and PSV<sub>L</sub>/PSV<sub>B</sub> demonstrated comparable AUCs in predicting ISR. However, the sensitivity and specificity of PSV<sub>L</sub>/PSV<sub>B</sub> in predicting ISR were 92.3 and 93.5%, respectively, demonstrating higher specificity with equivalent sensitivity than PSV<sub>L</sub> and higher sensitivity with equivalent specificity than RIR<sub>L</sub>.</p><p><strong>Conclusions: </strong>DUS is an accurate technique to identify TRA-ISR. We suggest all patients should undergo DUS immediately after stenting to establish baseline value and aid in evaluating ISR at late follow-up.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ultrasound in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jum.16656","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ACOUSTICS","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To evaluate the diagnosis performance of duplex ultrasound (DUS) in predicting transplanted renal artery (TRA) in-stent restenosis (ISR).
Methods: In this retrospective study, 112 consecutive patients underwent stenting due to TRA stenosis. DUS were performed within 1 week after stenting for baseline value, and after ≥3 months follow-up for surveillance of ISR. The DUS measurements included peak systolic velocity (PSV) and PSV ratio of renal artery stent to iliac artery (RIR). Receiver operating characteristic (ROC) curves were applied to evaluate the diagnosis performance of DUS parameters in predicting ISR.
Results: There were 69 patients (28 men; age, 38.3 ± 15.1 years) who obtained 92 adequate paired DUS and CTA after stenting, which were classified as ISR group (26 TRAs) and non-ISR group (66 TRAs). There was no difference between the two groups for baseline DUS features, including PSVB and RIRB. The late DUS features including stent PSVL (475.5 vs 261.9 cm/s), RIRL (4.10 vs 2.18), and stent PSVL/PSVB (2.72 vs 1.14) were significantly higher in the ISR group than the non-ISR group (all P < .0001). Stent PSVL, RIRL, and PSVL/PSVB demonstrated comparable AUCs in predicting ISR. However, the sensitivity and specificity of PSVL/PSVB in predicting ISR were 92.3 and 93.5%, respectively, demonstrating higher specificity with equivalent sensitivity than PSVL and higher sensitivity with equivalent specificity than RIRL.
Conclusions: DUS is an accurate technique to identify TRA-ISR. We suggest all patients should undergo DUS immediately after stenting to establish baseline value and aid in evaluating ISR at late follow-up.
期刊介绍:
The Journal of Ultrasound in Medicine (JUM) is dedicated to the rapid, accurate publication of original articles dealing with all aspects of medical ultrasound, particularly its direct application to patient care but also relevant basic science, advances in instrumentation, and biological effects. The journal is an official publication of the American Institute of Ultrasound in Medicine and publishes articles in a variety of categories, including Original Research papers, Review Articles, Pictorial Essays, Technical Innovations, Case Series, Letters to the Editor, and more, from an international bevy of countries in a continual effort to showcase and promote advances in the ultrasound community.
Represented through these efforts are a wide variety of disciplines of ultrasound, including, but not limited to:
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Breast Ultrasound-
Contrast-Enhanced Ultrasound-
Dermatology-
Echocardiography-
Elastography-
Emergency Medicine-
Fetal Echocardiography-
Gastrointestinal Ultrasound-
General and Abdominal Ultrasound-
Genitourinary Ultrasound-
Gynecologic Ultrasound-
Head and Neck Ultrasound-
High Frequency Clinical and Preclinical Imaging-
Interventional-Intraoperative Ultrasound-
Musculoskeletal Ultrasound-
Neurosonology-
Obstetric Ultrasound-
Ophthalmologic Ultrasound-
Pediatric Ultrasound-
Point-of-Care Ultrasound-
Public Policy-
Superficial Structures-
Therapeutic Ultrasound-
Ultrasound Education-
Ultrasound in Global Health-
Urologic Ultrasound-
Vascular Ultrasound