Correlation of retinal curvature with ocular biometry in patients with myopia

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-02-04 DOI:10.1016/j.pdpdt.2025.104505

Guo-Ren Xu , Ming Yan , Zhen Huang , Ya Ye , Yan-Ping Song

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引用次数: 0

Abstract

Purpose

To evaluate the relationship between retinal curvature (RC) and ocular biometry in patients with myopia.

Method

The clinical data of 74 patients with myopia (148 eyes) were retrospectively analyzed. Macular 24×20 mm optical coherence tomography (OCT) scans were acquired using an ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) system. The software then identified the Bruch's membrane and integrated it with the axial length (AL) for morphological correction, yielding a fitted three-dimensional retinal model. From this model, an RC map was generated, detailing the Gaussian curvature at each point. The maximum retinal curvature (RCmax) and central macular retinal curvature (RCc) were analyzed.

Results

A total of 148 eyes were analyzed. The analysis revealed that RCmax was negatively correlated with AL (r=-0.266, P < 0.05) and positively correlated with mean keratometry (Km) (r = 0.285, P < 0.05). RCc was also positively correlated with Km (r = 0.167, P < 0.05), whereas RCmax and RCc were positively correlated with each other (r = 0.450, P < 0.05).

Conclusions

In eyes with large innate eyeballs (characterized by a smaller Km), the RCmax was smaller, and acquired axial elongation (characterized by a larger AL) led to a reduction in RCmax, and vice versa. Eyes with large innate eyeballs also showed a smaller RCc, and vice versa.

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.