Paracoccidioidomycosis-related hospitalization and mortality rates in the state of São Paulo, Brazil: A study using socioeconomic, demographic, and climatic predictors.
Isabela Spinelli, Leandro Roberto de Macedo, Gabriella Freitas Ferreira
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引用次数: 0
Abstract
Paracoccidioidomycosis (PCM) is endemic in impoverished communities in Latin America. This study aimed to understand the impact of sociodemographic, economic, and climatic factors on the number of hospitalizations and deaths due to PCM in São Paulo (SP) state, Brazil. Data on 645 municipalities were collected from government databases between 2006 and 2020. The Spearman's correlations between sociodemographic variables (population density, Municipal Human Development Index, and number of public health facilities in the municipality) and PCM rates showed the strongest negative correlation coefficients among the other variables. Multiple regression models reinforced the influence of sociodemographic and climatic factors on PCM reports.
期刊介绍:
Medical Mycology is a peer-reviewed international journal that focuses on original and innovative basic and applied studies, as well as learned reviews on all aspects of medical, veterinary and environmental mycology as related to disease. The objective is to present the highest quality scientific reports from throughout the world on divergent topics. These topics include the phylogeny of fungal pathogens, epidemiology and public health mycology themes, new approaches in the diagnosis and treatment of mycoses including clinical trials and guidelines, pharmacology and antifungal susceptibilities, changes in taxonomy, description of new or unusual fungi associated with human or animal disease, immunology of fungal infections, vaccinology for prevention of fungal infections, pathogenesis and virulence, and the molecular biology of pathogenic fungi in vitro and in vivo, including genomics, transcriptomics, metabolomics, and proteomics. Case reports are no longer accepted. In addition, studies of natural products showing inhibitory activity against pathogenic fungi are not accepted without chemical characterization and identification of the compounds responsible for the inhibitory activity.