Mental health and psychological processes associated with cognitive aging and dementia.

IF 4.4 2区 医学 Q1 CLINICAL NEUROLOGY
Current Opinion in Neurology Pub Date : 2025-04-01 Epub Date: 2025-02-07 DOI:10.1097/WCO.0000000000001353
David Bartrés-Faz, Natalie L Marchant
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引用次数: 0

Abstract

Purpose of review: This review focuses on the role of psychological factors in cognitive aging and dementia, an area that has received less attention compared to other modifiable factors (e.g. sleep, physical activity, and so on) or reduction of disease risk.

Recent findings: A range of mental health and psychological aspects, including clinical symptoms, stable personality traits, and more specific constructs or processes (e.g. repetitive negative thinking, purpose in life), are associated with cognitive aging and dementia risk. Psychological factors can either serve as protective or risk elements, influencing brain health through general mechanisms, including stress regulation and impact on several biological systems, as well as modulate brain resistance and cognitive resilience to Alzheimer's disease and age-related brain changes. Protective psychological traits are linked to healthier lifestyle habits, while risk factors are associated with negative behaviors, and may impact cognitive function across the lifespan, suggesting benefits for psychological education from early life.

Summary: The review emphasizes the need for greater focus on optimizing psychological well being, particularly in at-risk populations, and suggests that interventions should be tailored to individuals' values and life purposes. Additionally, further research is needed to explore the neurobiological mechanisms through which psychologically focused interventions may influence cognitive decline and dementia.

与认知老化和痴呆相关的心理健康和心理过程。
综述目的:本综述的重点是心理因素在认知衰老和痴呆中的作用,与其他可调节因素(如睡眠、身体活动等)或降低疾病风险相比,这一领域受到的关注较少。最近的发现:一系列心理健康和心理方面,包括临床症状、稳定的人格特征和更具体的构念或过程(如重复的消极思维、生活目的),与认知老化和痴呆风险有关。心理因素既可以作为保护因素,也可以作为风险因素,通过一般机制影响大脑健康,包括压力调节和对几种生物系统的影响,以及调节大脑对阿尔茨海默病和与年龄相关的大脑变化的抵抗力和认知弹性。保护性心理特征与更健康的生活习惯有关,而风险因素与负面行为有关,并可能影响整个生命周期的认知功能,这表明从早期开始进行心理教育是有益的。摘要:该综述强调需要更多地关注优化心理健康,特别是在高危人群中,并建议干预措施应根据个人价值观和生活目标进行调整。此外,还需要进一步的研究来探索心理干预可能影响认知能力下降和痴呆的神经生物学机制。
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来源期刊
Current Opinion in Neurology
Current Opinion in Neurology 医学-临床神经学
CiteScore
8.60
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​Current Opinion in Neurology is a highly regarded journal offering insightful editorials and on-the-mark invited reviews; covering key subjects such as cerebrovascular disease, developmental disorders, neuroimaging and demyelinating diseases. Published bimonthly, each issue of Current Opinion in Neurology introduces world renowned guest editors and internationally recognized academics within the neurology field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.
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