Enantioselective effects of dinotefuran on physiological parameters in Rana nigromaculata tadpoles

IF 1.7 4区环境科学与生态学 Q3 ECOLOGY

Aquatic Ecology Pub Date : 2024-10-30 DOI:10.1007/s10452-024-10150-1

Fangze Li, Yu Wang, Xiaohuan Wang, Hui Jiao, Lulu Ran, Ping Lu

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引用次数: 0

Abstract

Dinotefuran possesses promising prospects, but poses a threat to the health of organisms in aquatic environment. In this study, the enantioselective toxicity effects of dinotefuran on Rana nigromaculata tadpoles were investigated. Acute toxicity tests for 96 h showed that R-(−)-dinotefuran had a more significant toxic effect on tadpoles than Rac-dinotefuran, which was greater than that of S-(+)-dinotefuran. In the toxicity assays with 0.2 and 2 mg/L dinotefuran for 28 d, noticeable changes in oxidative stress induced by Rac-dinotefuran and the two enantiomers were observed. The results of the growth parameters indicated that the development of R. nigromaculata tadpoles was inhibited to a certain extent, and the order was R-(-)-dinotefuran > Rac-dinotefuran > S-(+)-dinotefuran. Furthermore, the determination of triiodothyronine (T3) and thyroxine (T4), and the expression levels of corresponding genes (dio2, dio3, trα and trβ), demonstrated that R-(-)-dinotefuran and Rac-dinotefuran caused endocrine disruption of the thyroid system and delayed the development and metamorphosis of tadpoles, but S-(+)-dinotefuran had little effect, which was basically consistent with the results of acute toxicity and growth parameter assays. The results provide a new theoretical basis for assessing the environmental risk posed by chiral pesticides to aquatic nontargeted organisms.

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来源期刊

Aquatic Ecology 环境科学-海洋与淡水生物学

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Aquatic Ecology publishes timely, peer-reviewed original papers relating to the ecology of fresh, brackish, estuarine and marine environments. Papers on fundamental and applied novel research in both the field and the laboratory, including descriptive or experimental studies, will be included in the journal. Preference will be given to studies that address timely and current topics and are integrative and critical in approach. We discourage papers that describe presence and abundance of aquatic biota in local habitats as well as papers that are pure systematic. The journal provides a forum for the aquatic ecologist - limnologist and oceanologist alike- to discuss ecological issues related to processes and structures at different integration levels from individuals to populations, to communities and entire ecosystems.