Home noninvasive ventilation in pediatric patients: Does one size fit all?

IF 3.5 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Respiratory medicine Pub Date : 2025-02-06 DOI:10.1016/j.rmed.2025.107983

Sonia Khirani , Lucie Griffon , Alessandro Amaddeo , Florent Baudin , Priscille Bierme , Jessica Taytard , Nathalie Stremler , Melisande Baravalle-Einaudi , Julie Mazenq , Iulia Ioan , Cyril Schweitzer , Marie-Emilie Lampin , Alexandra Binoche , Clémence Mordacq , Jean Bergounioux , Blaise Mbieleu , Robert Rubinsztajn , Elodie Sigur , Géraldine Labouret , Arnaud Bécourt , Brigitte Fauroux

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引用次数: 0

Abstract

Background

A French national survey showed that 1447 children were treated with long-term continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in 2019. Data about the ventilatory settings for children are scarce. The aim of the study was to report the CPAP/NIV settings from the survey according to the patients’ age and disorders.

Methods

CPAP and NIV settings were compared between 5 age groups (<1, 1–5, 6–11, 12–17 and ≥ 18 years), and 6 disease categories (upper airway disorders; neuromuscular disease, NMD; disorder of the central nervous system; cardiorespiratory disorder; congenital bone disease, CBD; and other).

Results

Age correlated positively with constant CPAP pressure (r = 0.364, p < 0.0001), and negatively with CPAP adherence (r = −0.173, p < 0.0001). Mean age at CPAP initiation, CPAP pressures and adherence did not differ between disorders. Regarding NIV, mean inspiratory positive airway pressure (IPAP) increased with age (r = 0.152, p = 0.0001), whereas respiratory rate (RR; r = −0.593, p < 0.0001) and adherence to NIV decreased with age (r = −0.154, p = 0.0002). NIV settings were quite similar between disease categories, with the CBD group having the highest IPAP, and NMD group having the lowest expiratory positive airway pressure and RR. Adherence tended to be higher with NIV than CPAP.

Conclusions

CPAP pressure and IPAP increase with age, while settings seem quite similar between diseases. Even if our study provides some information about CPAP/NIV settings, they should always be individually adapted according to the severity of the disease.

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来源期刊

Respiratory medicine 医学-呼吸系统

CiteScore

7.50

自引率

0.00%

发文量

199

审稿时长

38 days

期刊介绍： Respiratory Medicine is an internationally-renowned journal devoted to the rapid publication of clinically-relevant respiratory medicine research. It combines cutting-edge original research with state-of-the-art reviews dealing with all aspects of respiratory diseases and therapeutic interventions. Topics include adult and paediatric medicine, epidemiology, immunology and cell biology, physiology, occupational disorders, and the role of allergens and pollutants. Respiratory Medicine is increasingly the journal of choice for publication of phased trial work, commenting on effectiveness, dosage and methods of action.