Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population

IF 2.4 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Preventive Medicine Reports Pub Date : 2025-02-01 DOI:10.1016/j.pmedr.2025.102994

Rena Rehemuding , Kaisaierjiang Kadier , Xinliang Peng , Pengfei Liu , Diliyaer Dilixiati , Aikeliyaer Ainiwaer , Xiaozhu Liu , Xiangtao Liu , Xiang Ma

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引用次数: 0

Abstract

Background and Objective: Abdominal aortic calcification (AAC) is a marker of cardiovascular disease and is associated with increased mortality in middle-aged and older populations. However, its relationship with frailty remains unclear.

Methods: Data were obtained from the 2013–2014 National Health and Nutrition Examination Survey. AAC was quantified using the Kauppila scoring system based on dual-energy X-ray absorptiometry. Frailty was assessed using the frailty index. Multivariable logistic regression models examined the association between AAC and frailty.

Results: A total of 2987 adults aged ≥40 years were included. Compared to individuals with an AAC-8 score of 0, low-risk (AAC-8 score = 1–2; OR: 1.24; 95 % CI, 1.00–1.53) and high-risk AAC (AAC-8 score ≥ 3; OR: 1.83; 95 % CI, 1.03–3.23) were associated with higher odds of frailty. Similarly, mild to moderate AAC (0 < AAC-24 score ≤ 6; OR: 1.26; 95 % CI, 1.03–1.54) and severe AAC (AAC-24 score > 6; OR: 1.79; 95 % CI, 1.07–2.99) showed positive associations with frailty.

Conclusions: Among middle-aged and older populations in the United States, there exists a positive correlation between AAC and frailty. Our findings suggest that the AAC score holds promise as a valuable tool for the early identification of frailty.

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来源期刊

Preventive Medicine Reports Medicine-Public Health, Environmental and Occupational Health

CiteScore

3.90

自引率

0.00%

发文量

353